Obid 500 mg (Tablet)
Unit Price: ৳ 4.00 (10 x 10: ৳ 400.00)
Strip Price: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Delta pharma ltd |
| Also available as |
Indications
- Treatment of type 2 diabetes mellitus
- Management of overweight patients
- First-line therapy after diet failure
- Monotherapy or combination therapy
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers basal and postprandial plasma glucose
- Improves insulin sensitivity
- Decreases hepatic glucose production
Dosage & Administration
- Individualized dosage based on effectiveness and tolerance
- Maximum recommended daily doses
- Immediate release tablet and extended release tablet options
- Dosing for adults and children
- Dosing adjustments for renal impaired patients
Interaction
- Potential interactions with Furosemide and Nifedipine
- Competing for renal tubular transport systems
- Impact on drugs that produce hyperglycemia
Contraindications
- Hypersensitivity to the active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Acute conditions altering renal function
- Conditions causing tissue hypoxia
Side Effects
- Hemolytic anemia
- Lactic acidosis
- Decrease of vitamin B12 absorption
- Taste disturbance
- Gastrointestinal disorders
- Liver function test abnormalities
- Skin reactions
Pregnancy & Lactation
- Uncontrolled diabetes risk during pregnancy
- Recommendation for insulin use during pregnancy
- Excretion into human breast milk
- Consideration for discontinuing breastfeeding
Precautions & Warnings
- Substantial excretion by the kidney
- Lowering of vitamin B12 level
- Increased risk of hypoglycemia
- Regular monitoring of renal function
- Special caution in elderly subjects
Use in Special Populations
- Dosage adjustment for elderly subjects
- Confirmation of type 2 diabetes mellitus before treatment
- Caution in children aged 10-12 years
- Regular assessment of renal function
- Impact on growth and puberty
Overdose Effects
- Lactic acidosis as a medical emergency
- Hypoglycemia not seen with certain doses
- Treatment via hemodialysis
Therapeutic Class
- Biguanides
Storage Conditions
- Temperature below 30°C
- Protection from light and moisture
- Keep out of the reach of children