Ruzmet 500 mg (Tablet)
Unit Price: ৳ 8.33 (30's pack: ৳ 250.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Amico laboratories ltd |
Indications
- Treatment of type 2 diabetes mellitus
- Management of type 2 diabetes in overweight patients
- Monotherapy for adults with diabetes
- Combination therapy for adults with diabetes
- Therapy for children from 10 years of age and adolescents
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers basal and postprandial plasma glucose
- Decreases hepatic glucose production
- Improves insulin sensitivity
Dosage & Administration
- Individualized dosage based on effectiveness and tolerance
- Dosing increments for adults and children
- Immediate release tablet dosing
- Extended release tablet dosing
- Dosage adjustment for renal impaired patients
Interaction
- No information available about Ruzmet and Furosemide interaction
- Enhanced absorption with Nifedipine
- Potential interaction with cationic drugs
- Effects on drugs causing hyperglycemia
Contraindications
- Hypersensitivity to active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Acute conditions altering renal function
- Conditions causing tissue hypoxia
Side Effects
- Hemolytic anemia
- Lactic acidosis
- Decrease of vitamin B12 absorption
- Neuropathy related to vitamin B12 deficiency
- Taste disturbance
- Gastrointestinal disorders
- Liver function test abnormalities
- Skin reactions
Pregnancy & Lactation
- Increased risk with uncontrolled diabetes during pregnancy
- Special precautions during breastfeeding
- Excretion of metformin in human breast milk
Precautions & Warnings
- Substantial excretion by the kidney
- Lowered vitamin B12 level
- Increased risk of hypoglycemia in combination therapy
- Need for monitoring renal function
- Recommendation for stopping therapy before surgery
Use in Special Populations
- Dosage adjustment in elderly subjects
- Confirmaion of type 2 diabetes mellitus in pediatrics
- No detected effect on growth and puberty
- Regular assessment of renal function
Overdose Effects
- Lactic acidosis as a medical emergency
- Hypoglycemia
- Removal of lactate and Ruzmet through hemodialysis
Therapeutic Class
- Biguanides
Storage Conditions
- Below 30°C temperature
- Protected from light & moisture