Lijenta 5 mg (Tablet)

Unit Price: ৳ 22.00 (2 x 15: ৳ 660.00)
Strip Price: ৳ 330.00

Medicine Details

Category Details
Generic Linagliptin
Company Nipro jmi pharma ltd

Title

  • Lijenta 5 mg Tablet

Categories

  • Medicine
  • Diabetes Treatment

Description

  • Lijenta is indicated in the treatment of type 2 diabetes mellitus to improve glycaemic control in adults.
  • Inhibitor of DPP-4 (dipeptidyl peptidase-4)

Dosage

Linagliptin 5 mg once daily. If added to metformin, the dose of metformin should be maintained and linagliptin administered concomitantly. When used in combination with a sulfonylurea, a lower dose of the sulphonylurea may be considered to reduce the risk of hypoglycaemia.

Pharmacology

Linagliptin is an inhibitor of DPP-4, an enzyme that degrades incretin hormones GLP-1 and GIP. It increases the concentrations of active incretin hormones, stimulating the release of insulin and decreasing the secretion of glucagon.

Mode of Action

Inhibitor of DPP-4 enzyme.

Indications

  • Type 2 diabetes mellitus in adults
  • Monotherapy for patients inadequately controlled by diet and exercise alone
  • Combination therapy with metformin or sulphonylurea and metformin

Interaction

Weak competitive and a weak to moderate mechanism-based inhibitor of CYP isozyme CYP3A4. Low risk for clinically meaningful interactions.

Contraindications

  • Hypersensitivity to the active substance or to any of the excipients

Side Effects

  • Hypoglycaemia
  • Nasopharyngitis
  • Cough
  • Pancreatitis in combination with metformin and sulfonylurea

Pregnancy & Lactation

  • Pregnancy category B
  • Should be used during pregnancy only if clearly needed. Unknown whether it passes into breast milk

Precautions & Warnings

  • Hypersensitivity to the active substance or to any of the excipients

Therapeutic Class

  • Dipeptidyl Peptidase-4 (DPP-4) inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C25H28N8O2

Common Questions

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  • What are the instructions for the storage and disposal of Lijenta 5 mg Tablet?
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