Ambozin 15 mg/5 ml (Syrup)

100 ml bottle: ৳ 40.00

Medicine Details

Indications

  • Productive cough
  • Acute and chronic inflammatory disorders of upper and lower respiratory tracts
  • Inflammatory disease of rhinopharyngeal tract
  • Asthmatic bronchitis
  • Bronchiectasis
  • Chronic pneumonia

Pharmacology

  • Ambroxol is the active metabolite of bromhexine
  • Greater bronchosecretolytic effect than bromhexine
  • Improves sputum rheology
  • Hydrating mechanism leading to liquefaction of mucus
  • Facilitates expectoration of mucus
  • Reduces dyspnea
  • Stimulates production of phospholipids of surfactant by alveolar cells
  • Contributes to lowering of superficial tension in the alveoli
  • Reduces bronchial hyperactivity
  • Anti-inflammatory properties

Dosage & Administration

  • Average daily dose
  • Pediatric Drops for different age groups
  • Syrup dosage for different age groups
  • Sustained release capsule dosage for adults and children over 12 years old

Interaction

  • Should not be taken simultaneously with antitussives (e.g. Codeine)

Contraindications

  • Known hypersensitivity to Ambroxol or Bromhexine

Side Effects

  • Gastrointestinal side effects
  • Allergic responses such as eruption, urticaria or angioneurotic edema

Pregnancy & Lactation

  • No harmful effect shown in teratogenic and fetal toxicity studies
  • Advised not to use in pregnancy, especially during the 1st trimester
  • Safety during lactation not established

Precautions & Warnings

  • Should be given cautiously to patients with gastric and duodenal ulceration or convulsive disorders
  • Patients with hepatic and renal insufficiency should take it with caution

Therapeutic Class

  • Cough expectorants & mucolytics

Storage Conditions

  • Protect from direct light exposure
  • Store in a dry place at a temperature not exceeding 30°C
  • Keep out of the reach of children

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