Janvia 50 mg (Tablet)
Unit Price: ৳ 15.04 (3 x 10: ৳ 451.20)
Strip Price: ৳ 150.40
Medicine Details
| Category | Details |
|---|---|
| Generic | Sitagliptin |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Adjunct to diet and exercise
- Improves glycemic control
- Type 2 diabetes mellitus only
Pharmacology
- DPP-4 inhibitor
- Increases and prolongs action of incretin hormones
- Regulates glucose homeostasis
Dosage & Administration
- Recommended dose of 50mg or 100mg daily
- Can be taken with or without food
Interaction
- No meaningful alteration in pharmacokinetics of certain drugs
- Slightly increases mean concentration of Digoxin
Contraindications
- History of serious hypersensitivity reaction to sitagliptin
Side Effects
- Common adverse reactions: headache, upper respiratory tract infection, nasopharyngitis
- Hypoglycemia with combination therapy
Pregnancy & Lactation
- Category B for pregnancy
- Secreted in the milk of lactating rats
- Caution during nursing
Precautions & Warnings
- Prompt discontinuation if pancreatitis is suspected
- Dosage adjustment in patients with renal insufficiency
- Use with medications known to cause hypoglycemia
- Hypersensitivity reaction precautions
Use in Special Populations
- Not established for pediatric patients under 18 years
- Dose selection and renal function assessment for elderly patients
- Different dosages for varying degrees of renal insufficiency
Overdose Effects
- Maximal mean increases in QTc observed at high doses
- Usual supportive measures for overdose
- Modestly dialyzable
Therapeutic Class
- Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Storage Conditions
- Store below 25°C
- Keep away from light
- Keep out of the reach of children
- Use before date of expiry
- Dispensed only on prescription