SGN 50 mg (Tablet)
Unit Price: ৳ 17.00 (3 x 10: ৳ 510.00)
Strip Price: ৳ 170.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sitagliptin |
| Company | Pacific pharmaceuticals ltd |
| Also available as |
Indications
- Adjunct to diet and exercise for type 2 diabetes mellitus
- Not for type 1 diabetes or diabetic ketoacidosis
Pharmacology
- DPP-4 inhibitor
- Increases and prolongs action of incretin hormones
- Regulates glucose homeostasis
- Increases insulin release and decreases glucagon levels
Dosage & Administration
- 50 mg twice a day
- 100 mg once daily
- Can be taken with or without food
Interaction
- No meaningful alteration in pharmacokinetics of certain drugs
- Slight increase in mean Digoxin concentration
Contraindications
- History of serious hypersensitivity reaction to sitagliptin
Side Effects
- Common adverse reactions include headache, upper respiratory tract infection, and nasopharyngitis
- Hypoglycemia in patients on combination therapy
Pregnancy & Lactation
- Pregnancy Category B
- Use during pregnancy only if clearly needed
- Excretion in lactating rats
Precautions & Warnings
- Prompt discontinuation if pancreatitis is suspected
- Dosage adjustment in patients with renal insufficiency
- Caution with medications known to cause hypoglycemia
- Reports of serious hypersensitivity reactions
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- Dose selection and renal function assessment in elderly patients
- Dosage adjustment based on renal insufficiency levels
Overdose Effects
- Modestly dialyzable
- Supportive measures recommended in case of overdose
Therapeutic Class
- Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Storage Conditions
- Store below 25°C in a dry place away from light
- Keep out of the reach of children
- Do not use later than the date of expiry
- Dispense only on prescription of a registered physician