Siglita 50 mg (Tablet)
Unit Price: ৳ 13.00 (2 x 10: ৳ 260.00)
Strip Price: ৳ 130.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sitagliptin |
| Company | Square pharmaceuticals plc |
Indications
- Adjunct to diet and exercise for type 2 diabetes mellitus
Pharmacology
- DPP-4 inhibitor
- Increases insulin release
- Decreases glucagon levels
- Regulates glucose homeostasis
Dosage & Administration
- Recommended dose of 50mg twice a day or 100mg once daily
- Can be taken with or without food
Interaction
- No meaningful alteration of pharmacokinetics for specific drugs
- Slight increase in mean Digoxin concentration
Contraindications
- History of serious hypersensitivity reaction to sitagliptin
Side Effects
- Common adverse reactions: headache, upper respiratory tract infection, nasopharyngitis
- Hypoglycemia risk with sulfonylurea and add on to insulin
Pregnancy & Lactation
- Pregnancy Category B
- Secreted in the milk of lactating rats
- Caution advised for nursing women
Precautions & Warnings
- Prompt discontinuation if pancreatitis is suspected
- Dosage adjustment in patients with renal insufficiency
- Caution with medications known to cause Hypoglycemia
- Reports of serious hypersensitivity reactions
Use in Special Populations
- Safety and effectiveness not established in pediatric patients under 18 years of age
- Dose adjustment and renal function assessment in elderly patients
- Different dosages for different levels of renal insufficiency
Overdose Effects
- Limited clinical adverse reactions up to 800mg doses
- Supportive measures for overdose management
- Modestly dialyzable
Therapeutic Class
- Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Storage Conditions
- Store below 25°C
- Store in a dry place away from light
- Keep out of the reach of children
- Do not use after expiry date
- Dispense only on prescription