Sitagil 25 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sitagliptin |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Adjunct to diet and exercise for type 2 diabetes mellitus
- Not indicated for type 1 diabetes
Pharmacology
- DPP-4 inhibitor
- Increases and prolongs action of incretin hormones
- Regulates glucose homeostasis
- Selective for DPP-4
Dosage & Administration
- Recommended dose: 50mg twice a day or 100mg once daily
- Can be taken with or without food
Interaction
- No meaningful alterations to various drug pharmacokinetics
- Slightly increases mean Digoxin concentration
Contraindications
- History of serious hypersensitivity reaction to sitagliptin
Side Effects
- Common adverse reactions: headache, upper respiratory tract infection, nasopharyngitis
- Hypoglycemia may occur in patients treated with sulfonylurea or insulin
Pregnancy & Lactation
- Pregnancy Category B
- Caution advised during lactation
Precautions & Warnings
- Prompt discontinuation if pancreatitis is suspected
- Dosage adjustment in patients with renal insufficiency
- Caution with medications known to cause hypoglycemia
- Reports of serious hypersensitivity reactions
Use in Special Populations
- Safety and effectiveness not established in pediatric patients under 18 years of age
- Careful dose selection in elderly patients with decreased renal function
- Dosage adjustment in patients with renal insufficiency
Overdose Effects
- Maximal mean QTc increases observed at high doses
- Supportive measures recommended in case of overdose
- Modestly dialyzable
Therapeutic Class
- Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Storage Conditions
- Store below 25°C in a dry place away from light
- Keep out of reach of children
- Dispensed only on prescription