Sitagil 100 mg (Tablet)
Unit Price: ৳ 28.00 (3 x 10: ৳ 840.00)
Strip Price: ৳ 280.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sitagliptin |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Adjunct to diet and exercise for type 2 diabetes mellitus
- Improves glycemic control in adults
Pharmacology
- DPP-4 inhibitor
- Slows inactivation of incretin hormones
- Increases insulin release
- Decreases glucagon levels
Dosage & Administration
- 50 mg twice a day
- 100 mg once daily
- Can be taken with or without food
Interaction
- No meaningful alteration of pharmacokinetics for specific drugs
- Slightly increases mean Digoxin concentration
Contraindications
- History of serious hypersensitivity reaction to sitagliptin
Side Effects
- Common adverse reactions include headache, upper respiratory tract infection, and nasopharyngitis
- Hypoglycemia may occur in patients treated with combination of Sitagil and sulfonylurea
Pregnancy & Lactation
- Pregnancy Category B
- Should be used during pregnancy only if clearly needed
- Caution should be exercised when administered to a nursing woman
Precautions & Warnings
- Prompt discontinuation if pancreatitis is suspected
- Dosage adjustment recommended in patients with renal insufficiency
- Use with caution in patients with history of hypersensitivity reactions
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- Careful dose selection in elderly patients with decreased renal function
Overdose Effects
- Maximal mean increases in QTc of 8.0 msec observed at high doses
- Supportive measures recommended in the event of overdose
Therapeutic Class
- Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Storage Conditions
- Store below 25°C
- Keep away from light
- Keep out of the reach of children
- Do not use after expiry date
- To be dispensed only on prescription of a registered physician