Sliptin 25 mg (Tablet)
Unit Price: ৳ 8.05 (3 x 14: ৳ 338.10)
Strip Price: ৳ 112.70
Medicine Details
| Category | Details |
|---|---|
| Generic | Sitagliptin |
| Company | Drug international ltd |
| Also available as |
Indications
- Adjunct to diet and exercise for type 2 diabetes mellitus
- Limitations of use for Sliptin
- Not studied in patients with a history of pancreatitis
Pharmacology
- DPP-4 inhibitor
- Action on incretin hormones
- Regulation of glucose homeostasis
- GLP-1 and GIP hormonal effects
- Selective for DPP-4
Dosage & Administration
- Recommended dosage of 50mg twice a day or 100mg once daily
- Can be taken with or without food
Interaction
- Effects on other drugs
- No meaningful alteration in pharmacokinetics of specific drugs
- Slight increase in mean Digoxin concentration
Contraindications
- History of serious hypersensitivity reaction to sitagliptin
Side Effects
- Common adverse reactions
- Possibility of hypoglycemia
- Specific adverse reactions by combination therapy
Pregnancy & Lactation
- Pregnancy Category B
- Excretion in the milk of lactating rats
- Caution in administration to nursing women
Precautions & Warnings
- Prompt discontinuation if pancreatitis is suspected
- Dosage adjustment in patients with renal insufficiency
- Use with medications known to cause hypoglycemia
- Hypersensitivity reactions post-marketing reports
Use in Special Populations
- Safety and effectiveness in pediatric patients
- Dosing considerations for elderly and renal insufficiency patients
Overdose Effects
- Maximal mean increases in QTc observed
- Supportive measures in case of overdose
- Modest dialyzability
Therapeutic Class
- Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Storage Conditions
- Temperature and light storage recommendations
- Safe storage away from children
- Dispensing only on prescription