Sliptin 50 mg (Tablet)
Unit Price: ৳ 15.00 (2 x 14: ৳ 420.00)
Strip Price: ৳ 210.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sitagliptin |
| Company | Drug international ltd |
| Also available as |
Indications
- Improves glycemic control in adults with type 2 diabetes mellitus
- Adjunct to diet and exercise
- Not for use in patients with type 1 diabetes
- Not for the treatment of diabetic ketoacidosis
- Not studied in patients with a history of pancreatitis
Pharmacology
- DPP-4 inhibitor
- Slows inactivation of incretin hormones
- Increases and prolongs action of incretin hormones
- Increases insulin release and decreases glucagon levels in a glucose-dependent manner
Dosage & Administration
- Recommended dose of 50 mg twice a day
- Recommended dose of 100 mg once daily
- Can be taken with or without food
Interaction
- Does not meaningfully alter the pharmacokinetics of certain drugs
- Slightly increases mean digoxin concentration
Contraindications
- History of serious hypersensitivity reaction to sitagliptin
Side Effects
- Common adverse reactions include headache, upper respiratory tract infection, and nasopharyngitis
- Hypoglycemia may occur in patients treated with combination to Sliptin and sulfonylurea as an add-on to insulin
Pregnancy & Lactation
- Pregnancy Category B
- Should be used during pregnancy only if clearly needed
- Caution should be exercised when administered to a nursing woman
Precautions & Warnings
- Prompt discontinuation if pancreatitis is suspected
- Dosage adjustment recommended in patients with renal insufficiency
- Caution when used with medications known to cause hypoglycemia
- Reports of serious hypersensitivity reactions
- Safety and effectiveness in pediatric patients under 18 years of age not established
- Caution in dose selection in elderly patients with decreased renal function
Use in Special Populations
- Safety and effectiveness in pediatric patients under 18 years of age not established
- Caution in dose selection in elderly patients with decreased renal function
Overdose Effects
- Maximal mean increases in QTc of 8.0 msec observed in one study at a dose of 800 mg
- No dose-related clinical adverse reactions observed with doses of up to 600 mg per day
- Modestly dialyzable
- Supportive measures recommended in the event of an overdose
Therapeutic Class
- Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Storage Conditions
- Store below 25°C in a dry place away from light
- Keep the medicines in a safe place, out of the reach of children
- Do not use later than the date of expiry
- To be dispensed only on the prescription of a registered physician