Silinor 50 mg (Tablet)
Unit Price: ৳ 18.00 (3 x 10: ৳ 540.00)
Strip Price: ৳ 180.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sitagliptin |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- Adjunct to diet and exercise for type 2 diabetes mellitus
Pharmacology
- DPP-4 inhibitor
- Increases and prolongs action of incretin hormones
- Regulates glucose homeostasis
Dosage & Administration
- Recommended dose of 50mg twice a day or 100mg once daily
- Can be taken with or without food
Interaction
- Did not alter the pharmacokinetics of certain drugs
- Slightly increases concentration of Digoxin
Contraindications
- History of serious hypersensitivity reaction to sitagliptin
Side Effects
- Common adverse reactions include headache, upper respiratory tract infection, and nasopharyngitis
- Hypoglycemia may occur in certain patients
Pregnancy & Lactation
- Pregnancy Category B
- Excreted in the milk of lactating rats
Precautions & Warnings
- Prompt discontinuation if pancreatitis is suspected
- Dosage adjustment in renal insufficiency
- Caution with medications known to cause hypoglycemia
- Risk of hypersensitivity reactions
Use in Special Populations
- Safety and effectiveness not established in pediatric patients under 18 years
- Dose adjustment in elderly and patients with renal insufficiency
Overdose Effects
- Maximal mean increase in QTc observed at high doses
- Supportive measures and clinical monitoring for overdose
Therapeutic Class
- Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Storage Conditions
- Store below 25°C in a dry place away from light
- Keep out of reach of children
- Use before date of expiry