Sitap 50 mg (Tablet)
Unit Price: ৳ 18.00 (3 x 10: ৳ 540.00)
Strip Price: ৳ 180.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sitagliptin |
| Company | Aci limited |
| Also available as |
Indications
- Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus
Pharmacology
- DPP-4 inhibitor
- Increases and prolongs action of incretin hormones
- Regulates glucose homeostasis
Dosage & Administration
- 50 mg twice a day
- 100 mg once daily
- Can be taken with or without food
Interaction
- Did not meaningfully alter the pharmacokinetics of certain drugs
- Slightly increases mean concentration of Digoxin
Contraindications
- History of serious hypersensitivity reaction to sitagliptin
Side Effects
- Headache
- Upper respiratory tract infection
- Nasopharyngitis
- Hypoglycemia risk in combination therapy
Pregnancy & Lactation
- Pregnancy Category B
- Secreted in the milk of lactating rats
Precautions & Warnings
- Prompt discontinuation if pancreatitis is suspected
- Dosage adjustment in renal insufficiency
- Use with caution in patients on medications known to cause Hypoglycemia
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- Greater caution in dose selection for elderly patients with decreased renal function
Overdose Effects
- Maximal mean increase in QTc observed in controlled clinical trials
- No dose-related clinical adverse reactions observed with doses up to 600 mg per day
Therapeutic Class
- Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Storage Conditions
- Store below 25°C in a dry place away from light
- Keep out of reach of children
- Dispensed only on prescription of a registered physician