Sitavia 50 mg (Tablet)

Unit Price: ৳ 15.00 (2 x 10: ৳ 300.00)
Strip Price: ৳ 150.00

Medicine Details

Category Details
Generic Sitagliptin
Company Sharif pharmaceuticals ltd

Indications

  • Adjunct to diet and exercise
  • Improves glycemic control in adults with type 2 diabetes mellitus

Pharmacology

  • DPP-4 inhibitor
  • Slows inactivation of incretin hormones
  • Increases and prolongs action of incretin hormones
  • Increases insulin release and decreases glucagon levels in circulation

Dosage & Administration

  • Recommended dose of 50 mg twice a day
  • Can be taken with or without food

Interaction

  • Did not meaningfully alter the pharmacokinetics of various drugs
  • Slightly increases mean Digoxin concentration

Contraindications

  • History of serious hypersensitivity reaction to sitagliptin

Side Effects

  • Common adverse reactions include headache, upper respiratory tract infection, and nasopharyngitis
  • Hypoglycemia may occur in patients treated with the combination to Sitavia and sulfonylurea and add on to insulin

Pregnancy & Lactation

  • Pregnancy Category B
  • Caution should be exercised when administered to a nursing woman

Precautions & Warnings

  • Should be promptly discontinued if pancreatitis is suspected
  • Dosage adjustment is recommended in patients with renal insufficiency
  • Caution should be exercised when used with medications known to cause Hypoglycemia

Use in Special Populations

  • Safety and effectiveness in pediatric patients under 18 years of age have not been established
  • Care should be taken in dose selection in the elderly

Overdose Effects

  • No experience with doses above 800 mg in clinical studies
  • Modestly dialyzable
  • Prolonged hemodialysis may be considered if clinically appropriate

Therapeutic Class

  • Dipeptidyl Peptidase-4 (DPP-4) inhibitor

Storage Conditions

  • Store below 25°C in a dry place away from light
  • Keep the medicines in a safe place, out of the reach of children
  • Do not use later than the date of expiry
  • To be dispensed only on the prescription of a registered physician

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