Viglita 50 mg (Tablet)
Unit Price: ৳ 16.00 (2 x 10: ৳ 320.00)
Strip Price: ৳ 160.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Vildagliptin |
| Company | Square pharmaceuticals plc |
Indications
- Adjunct to diet and exercise
- Improves glycemic control
- Type 2 diabetes mellitus
- Monotherapy
- Dual combination with Metformin
- Sulphonylurea
- Thiazolidinedione
- Insulin
- Inadequate glycemic control
Pharmacology
- Dipeptidyl peptidase-4 (DPP-4) inhibitor
- Incretin hormones regulation
- GLP-1 and GIP hormone activation
- Insulin synthesis and release
- Glucagon secretion reduction
- Glucose-dependent manner
Dosage & Administration
- Recommended dose of 50mg or 100mg daily for monotherapy
- 50mg twice daily in dual combination with Metformin or Thiazolidinedione
- 50mg once daily in dual combination with Sulphonylurea
- May be taken with or without a meal
- No dosage adjustment in elderly or mild renal impairment
- Not recommended for pediatric use
Interaction
- No interactions with pioglitazone, metformin, glibenclamide, digoxin, warfarin, amlodipine, ramipril, valsartan, simvastatin
- Potential reduction of glucose-lowering effect with certain active substances: thiazides, corticosteroids, thyroid products, sympathomimetics
Contraindications
- Hypersensitivity to active substance or excipients
- Moderate to severe renal impairment
- Hepatic impairment
- Type 1 diabetes
Side Effects
- Majority of adverse reactions are mild and transient
- Rare case of hepatic dysfunction
- No additional safety signals in long-duration trials
Pregnancy & Lactation
- Not to be used in pregnancy
- Not to be used during lactation
Precautions & Warnings
- Caution in patients aged 75 years and older
- Liver function test (LFT) monitoring
- Transaminase levels monitoring
- Jaundice or other signs of liver dysfunction observation
- Limited experience in congestive heart failure patients
- Avoid use in NYHA functional class III-IV
Therapeutic Class
- Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Storage Conditions
- Store below 30°C
- Keep away from light and moisture
- Keep out of reach of children