Nomopil 1 mg (Tablet)

Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00

Medicine Details

Category Details
Generic Repaglinide
Company Incepta pharmaceuticals ltd
Also available as
Nomopil 05 mg tablet Nomopil 2 mg tablet

Indications

  • Adjunct to diet and exercise for lowering blood glucose in type 2 diabetes mellitus (NIDDM)
  • Indicated for use in combination with Metformin
  • Lower blood glucose in patients not controlled by exercise and diet alone

Description

  • Oral blood-glucose-lowering drug
  • Belongs to the meglitinide class
  • Management of Type 2 diabetes mellitus (NIDDM)

Pharmacology

  • Binds to specific receptors in the cell membrane
  • Leads to the closure of ATP dependent K+ channels
  • Stimulates insulin secretion
  • Causes pancreas to release more insulin into the bloodstream

Dosage & Administration

  • Starting dose should be 0.5 mg before each meal for some patients
  • Initial dose is 1 or 2 mg before each meal for others
  • Should be taken immediately or up to 30 minutes before each meal
  • Dosage adjustment should be according to response at intervals of 1-2 weeks

Interaction

  • Possible interactions with inhibitors and inducers of the cytochrome P450 enzyme system
  • No significant effect on Digoxin, Theophyllin, or Warfarin
  • Increased risk of hypoglycemia when co-administered with certain drugs

Contraindications

  • Contraindicated in diabetic ketoacidosis
  • Contraindicated in type 1 diabetes mellitus
  • Contraindicated in known hypersensitivity to the drug or its inactive ingredients

Side Effects

  • Most common side effects include hypoglycemia, upper respiratory tract infections, diarrhea, constipation, nausea, vomiting
  • Hypersensitivity reactions include rashes and urticaria

Pregnancy & Lactation

  • Safety in pregnant women not established
  • Should be used during pregnancy only if clearly needed
  • Not known whether Repaglinide is excreted in human milk
  • A decision should be made whether to discontinue nursing or the drug

Precautions & Warnings

  • Insulin should be substituted during concurrent illness
  • All oral blood glucose-lowering drugs can produce hypoglycemia
  • Should be administered with meals to lessen the risk of hypoglycemia

Overdose Effects

  • Patients receiving high doses developed few adverse effects other than lowering of blood glucose
  • Severe hypoglycemic reactions with coma, seizure or other neurological impairment occur infrequently

Therapeutic Class

  • Meglitinide Analogues

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

Related Brands