Ogli 15 mg (Tablet)
Unit Price: ৳ 8.03 (30's pack: ৳ 240.90)
Medicine Details
| Category | Details |
|---|---|
| Generic | Pioglitazone |
| Company | Kemiko pharmaceuticals ltd |
Indications
- Adjunct to diet and exercise
- Improves glycaemic control in patients with type II diabetes
- Monotherapy
- Combination therapy
Pharmacology
- Thiazolidinedione class of oral antidiabetic agent
- Depends on the presence of Insulin for its mechanism of action
- Decreases Insulin resistance
- Increases Insulin dependent glucose disposal
- Activates peroxisome proliferator activated receptor gamma (PPAR-γ)
Dosage & Administration
- Taken once daily
- Can be taken without regard to meals
- Individualized management of antidiabetic therapy
- Initiate at 15 mg or 30 mg once daily
- Maximum recommended daily dose is 45 mg
Interaction
- Reduces plasma concentration of oral contraceptive containing ethinyl oestradiol and norethindrone by approximately 30%
Contraindications
- Known hypersensitivity to any of its components
Side Effects
- Incidence and types of adverse events reported in placebo controlled clinical trials
- Occurrence of upper respiratory tract infection, headache, sinusitis, myalgia, tooth disorder, pharyngitis
Pregnancy & Lactation
- Use during pregnancy if potential benefit justifies potential risk to the foetus
- Not known whether Pioglitazone is secreted in human milk
- Not recommended for lactating women
Precautions & Warnings
- Not to be used in Type 1 diabetes or for the treatment of diabetic ketoacidosis
- Use with caution in case of combination antidiabetic therapy and hepatic insufficiency
- Regular monitoring of liver enzymes
Therapeutic Class
- Thiazolidinedione Group
Storage Conditions
- Store at 25° C