Piglit 15 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pioglitazone |
| Company | Pacific pharmaceuticals ltd |
Indications
- Adjunct to diet and exercise for type II diabetes
- Improves glycaemic control
- Monotherapy option
- Combination therapy option
- Use with sulphonylurea, Metformin, or Insulin
Pharmacology
- Oral antidiabetic agent
- Thiazolidinediones class member
- Depends on Insulin for action
- Decreases Insulin resistance
- Increases Insulin dependent glucose disposal
- Decreases hepatic glucose output
- Improves abnormality in lipid metabolism
- Activates peroxisome proliferator activated receptor gamma (PPAR-γ)
Dosage & Administration
- Once daily dosage
- Can be taken without regard to meals
- Individualized therapy management
- Initiation at 15 mg or 30 mg once daily
- Maximum recommended dose of 45 mg once daily
- Consider combination therapy for inadequate response
- Maximum dose of 45 mg for combination therapy
Interaction
- Reduces plasma concentration of oral contraceptives
- Reduces plasma concentration of ethinyl oestradiol and norethindrone by approximately 30%
Contraindications
- Hypersensitivity to any components
Side Effects
- Incidence of adverse events in clinical trials
- Upper respiratory tract infection
- Headache
- Sinusitis
- Myalgia
- Tooth disorder
- Pharyngitis
Pregnancy & Lactation
- Use during pregnancy if potential benefit justifies potential risk to the fetus
- Unknown secretion in human milk
- Not recommended during lactation due to potential excretion in human milk
Precautions & Warnings
- Exerts antihyperglycaemic effect only in the presence of Insulin
- Not for Type 1 diabetes or diabetic ketoacidosis treatment
- Caution in combination therapy and hepatic insufficiency
- Regular liver enzyme monitoring
Therapeutic Class
- Thiazolidinedione Group
Storage Conditions
- Store at 25°C