Piozena 15 mg (Tablet)

Indications

• Adjunct to diet and exercise for type II diabetes
• Monotherapy for glycaemic control

Pharmacology

• Belongs to thiazolidinediones class
• Dependent on the presence of Insulin for its mechanism of action
• Decreases Insulin resistance
• Increases Insulin-dependent glucose disposal

Dosage & Administration

• Can be taken once daily
• May be initiated at 15 mg or 30 mg once daily dosages
• Maximum recommended daily dose is 45 mg

Interaction

• Reduces plasma concentration of oral contraceptives

Contraindications

• Known hypersensitivity to any components

Side Effects

• Incidence of adverse events in placebo-controlled trials
• Common adverse events include upper respiratory tract infection, headache, sinusitis, myalgia

Pregnancy & Lactation

• Use during pregnancy only if potential benefit justifies potential risk to fetus
• Not known whether it is secreted in human milk

Precautions & Warnings

• Exerts antihyperglycaemic effect only in presence of Insulin
• Should not be used in Type 1 diabetes or for treatment of diabetic ketoacidosis
• Use with caution in case of combination antidiabetic therapy and hepatic insufficiency

Therapeutic Class

• Thiazolidinedione Group

Storage Conditions

• Store at 25°C

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