Glipita-M 50 mg+1000 mg (Tablet)
Unit Price: ৳ 18.00 (3 x 10: ৳ 540.00)
Strip Price: ৳ 180.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sitagliptin metformin hydrochloride |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Title
- Combination Oral Hypoglycemic Tablet
Categories
- Medicine
- Diabetes Management
- Pharmacology
Description
- This tablet is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both sitagliptin and metformin is appropriate.
Color Options
- Film-coated tablet: White
- Extended-release tablet: Yellow
Dimensions
- Film-coated tablet: 9mm x 5mm x 3mm
- Extended-release tablet: 10mm x 6mm x 3mm
Functions
- Improves glycemic control
- Combines two antihyperglycemic agents with complementary mechanisms of action
Materials
- Metformin HCl
- Sitagliptin
- Biguanide class
Technical Specifications
- Maximum recommended daily dose: 100 mg sitagliptin and 2000 mg metformin
Dosage & Administration
- Should generally be given twice daily with meals
- Individualized dosage based on patient's current regimen, effectiveness, and tolerability
- Starting dose based on patient's current regimen
Usability Features
- Gradual dose escalation reduces gastrointestinal side effects
- Administer the extended-release tablet once daily with a meal
Interaction
- Cationic drugs should be used with caution
Contraindications
- Contraindicated in patients with renal disease or dysfunction
- Acute or chronic metabolic acidosis
- Hypersensitivity reaction to the tablet or sitagliptin
Side Effects
- Common adverse reactions include diarrhea, upper respiratory tract infection, and headache
Pregnancy & Lactation
- Pregnancy Category B
- Caution during lactation
Precautions & Warnings
- Lactic acidosis risk
- Regular monitoring of thyroid-stimulating hormone levels recommended
- Monitoring of vitamin B12 level recommended
- Postmarketing reports of acute renal failure and pancreatitis
Overdose Effects
- Sitagliptin: Employ usual supportive measures in the event of overdose
- Metformin hydrochloride: Overdose has occurred, dialyzable with clearance of up to 170 mL/min
Therapeutic Class
- Combination Oral hypoglycemic preparations
Storage Conditions
- Store below 25°C in a dry place away from light, out of the reach of children