Sliptin-M 50 mg+1000 mg (Tablet)

Unit Price: ৳ 19.00 (2 x 7: ৳ 266.00)
Strip Price: ৳ 133.00

Medicine Details

Category Details
Generic Sitagliptin metformin hydrochloride
Company Drug international ltd
Also available as
Sliptin m 50 mg tablet Sliptin m er 50 mg tablet Sliptin m er 50 mg tablet

Indications

  • Adjunct to diet and exercise for type 2 diabetes mellitus
  • Improves glycemic control
  • Limitations of use for type 1 diabetes and diabetic ketoacidosis
  • Not studied in patients with a history of pancreatitis

Pharmacology

  • Combines sitagliptin and metformin
  • Antihyperglycemic agents
  • Complementary mechanisms of action
  • Inactivation of incretin hormones

Dosage & Administration

  • Individualized dosage
  • Maximum recommended daily dose
  • Gradual dose escalation with meals
  • Different doses for patients not currently treated with metformin and those already treated with metformin
  • Extended-release tablet dosing

Interaction

  • Cationic drug caution
  • Phenprocoumon interaction
  • Levothyroxine interaction

Contraindications

  • Renal disease or dysfunction
  • Acute or chronic metabolic acidosis
  • History of serious hypersensitivity reaction
  • Iodinated contrast materials

Side Effects

  • Common adverse reactions
  • Adverse reactions with sulfonylurea and insulin
  • Adverse reactions with sitagliptin monotherapy
  • Adverse reactions due to metformin therapy

Pregnancy & Lactation

  • Pregnancy Category B
  • Caution for nursing women

Precautions & Warnings

  • Lactic Acidosis risk factors and symptoms
  • Thyroid-stimulating hormone monitoring
  • Vitamin B12 level monitoring
  • Hepatic disease caution
  • Renal function assessment
  • Acute pancreatitis monitoring
  • Hematologic parameters monitoring
  • Alcohol intake warning
  • Insulin use during stress
  • Allergic and hypersensitivity reactions monitoring
  • Macrovascular risk reduction evidence

Overdose Effects

  • Sitagliptin overdose management
  • Modestly dialyzable sitagliptin
  • Metformin hydrochloride overdose management
  • Dialyzable metformin hydrochloride
  • Pancreatitis risk with metformin overdose

Therapeutic Class

  • Oral hypoglycemic preparations

Storage Conditions

  • Store below 25°C
  • Dry place away from light
  • Keep out of the reach of children
  • Do not use after expiry date
  • Dispensed only on prescription

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