Siglimet XR 50 mg+1000 mg (Tablet (Extended Release))

Unit Price: ৳ 18.00 (3 x 6: ৳ 324.00)
Strip Price: ৳ 108.00

Medicine Details

Category Details
Generic Sitagliptin metformin hydrochloride
Company Square pharmaceuticals plc
Also available as
Siglimet 50 mg tablet Siglimet 50 mg tablet Siglimet xr 50 mg tablet Siglimet xr 100 mg tablet

Indications

  • Adjunct to diet and exercise for type 2 diabetes mellitus
  • Improves glycemic control
  • Suitable for adults

Pharmacology

  • Combines sitagliptin and metformin
  • DPP-4 inhibitor
  • Biguanide class member
  • Incretin hormones regulation
  • Glucose homeostasis regulation

Dosage & Administration

  • Film-coated tablet
  • Individualized dosage
  • Twice daily with meals
  • Gradual dose escalation
  • Extended-release tablet option
  • Dosing adjustment for insulin users

Interaction

  • Cationic drugs caution
  • Phenprocoumon interaction
  • Levothyroxine interaction

Contraindications

  • Renal disease or dysfunction
  • Metabolic acidosis history
  • Hypersensitivity reaction history
  • Intravascular iodinated contrast materials usage

Side Effects

  • Diarrhea
  • Upper respiratory tract infection
  • Headache
  • Hypoglycemia
  • Nasopharyngitis
  • Nausea/vomiting
  • Fatulence
  • Abdominal discomfort
  • Indigestion
  • Asthenia

Pregnancy & Lactation

  • Category B for pregnancy
  • No adequate studies in pregnant women
  • Caution during nursing

Precautions & Warnings

  • Lactic acidosis risk factors
  • Hepatic disease caution
  • Renal function assessment
  • Pancreatitis risk monitoring
  • Vitamin B12 level monitoring
  • Alcohol intake warning
  • Insulin use during stress periods

Overdose Effects

  • Sitagliptin overdose measures
  • Metformin hydrochloride overdose measures
  • Dialysis considerations

Therapeutic Class

  • Combination Oral hypoglycemic preparations

Storage Conditions

  • Store below 25°C
  • Keep away from light
  • Keep out of reach of children
  • Dispense on physician's prescription

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