Viglimet 50 mg+850 mg (Tablet)

Unit Price: ৳ 22.00 (5 x 6: ৳ 660.00)
Strip Price: ৳ 132.00

Medicine Details

Category Details
Generic Vildagliptin metformin hydrochloride
Company Square pharmaceuticals plc
Also available as
Viglimet 50 mg tablet

Indications

  • Adjunct to diet and exercises
  • Improving glycaemic control
  • Type 2 diabetes mellitus

Pharmacology

  • Inhibition of DPP-4 enzyme
  • Increase in incretin hormones GLP-1 and GIP
  • Insulin secretion from pancreatic beta cell
  • Decrease in glucagon secretion from alpha cell
  • Reduction in hepatic glucose production

Dosage & Administration

  • Initiation based on current Metformin dose
  • Twice daily administration
  • Switching from separate tablets
  • No clinical experience in triple combination with other antidiabetic agents
  • Reduced gastrointestinal symptoms with food intake

Interaction

  • No clinically relevant pharmacokinetic interaction observed
  • Low potential for drug interactions
  • Not a cytochrome P (CYP) 450 enzyme substrate
  • No clinically relevant interactions with certain oral antidiabetics and other medications

Contraindications

  • Known hypersensitivity to components
  • Renal disease or dysfunction
  • Acute myocardial infarction
  • Septicaemia
  • Congestive heart failure
  • Metabolic acidosis and diabetic ketoacidosis
  • Use before radiologic studies involving intravascular administration of iodinated contrast materials

Side Effects

  • Headache
  • Tremor
  • Dizziness
  • Nausea
  • Hypoglycaemia

Pregnancy & Lactation

  • No adequate and well controlled studies in pregnant women
  • Potential benefit justifying potential risk to the foetus
  • Unknown excretion in human milk

Precautions & Warnings

  • Lactic acidosis risk
  • Serum creatinine monitoring in patients
  • Caution in elderly patients and with certain medications
  • Liver Function Tests (LFTs) monitoring
  • Discontinuation before elective surgery with general anaesthesia

Use in Special Populations

  • Not recommended for pediatric patients
  • Regular renal function monitoring in elderly patients
  • Contraindicated in patients with renal or hepatic impairment

Therapeutic Class

  • Combination Oral hypoglycemic preparations

Storage Conditions

  • Dry place away from light and heat
  • Keep out of the reach of children

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