Thyrox 50 mcg (Tablet)

Unit Price: ৳ 2.20 (3 x 30: ৳ 198.00)

Medicine Details

Indications

  • Replacement therapy in hypothyroidism
  • Suppression of TSH levels
  • Diagnostic aid in suppression tests

Pharmacology

  • Contains synthetic Levothyroxine (T4)
  • Conversion of T4 to T3 in peripheral tissues
  • TBG as major carrier of T4
  • Long half-life in circulation
  • Enterohepatic circulation of Thyroid hormones

Dosage & Administration

  • Initial starting dose: 25-50 mcg/day for adults
  • Pediatric dosage based on age and clinical response
  • Titration for secondary or tertiary hypothyroidism
  • Adjustment based on clinical response and laboratory parameters

Interaction

  • Concurrent use with tri/tetracyclic antidepressants
  • Administration with antidiabetic or insulin therapy
  • Monitoring of digitalis glycoside levels

Contraindications

  • Untreated subclinical or overt Thyrotoxicosis
  • Acute Myocardial Infarction
  • Uncorrected Adrenal failure

Side Effects

  • Adverse reactions primarily related to hyperthyroidism
  • Includes symptoms such as fatigue, weight loss, nervousness, palpitations

Pregnancy & Lactation

  • Category A in pregnancy
  • Caution advised for nursing women
  • Adequate replacement doses needed for normal lactation

Precautions & Warnings

  • Adrenocortical insufficiency in pituitary gland function decrease
  • Careful dosing for cardiovascular disease patients
  • Dosage adjustment based on body weight changes

Overdose Effects

  • Signs and symptoms of hyperthyroidism
  • Symptomatic treatment for overdose

Therapeutic Class

  • Thyroid drugs & hormone

Storage Conditions

  • Store below 30°C, protect from light

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