Carbiroid 5 mg (Tablet)
Unit Price: ৳ 4.80 (100's pack: ৳ 480.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Carbimazole |
| Company | The white horse pharmaceuticals ltd |
Indications
- Management of hyperthyroidism
- Management of thyrotoxicosis
- Preparation for thyroidectomy
Pharmacology
- Depresses formation of thyroid hormone
- Reduces uptake of inorganic iodine
- Metabolized to methimazole
- Crosses placental barrier and milk of lactating patients
Dosage & Administration
- Initial dose: 20-60 mg in divided doses
- Maintenance regimen: 5-15 mg/day
- Neonates & Children below 12 years: usual initial dose is 250 mcg/kg/day
- Duration of treatment: 18 to 24 months
Interaction
- May interact adversely with other medicines
- Iodine excess may decrease response
- Thioamide-induced hypoprothrombinemia may occur
- Increase in serum concentrations of digoxin and digitoxin
Contraindications
- Hypersensitivity to carbimazole or other thiourea antithyroid agents
Side Effects
- Rash
- Pruritis
- Gastro-intestinal disturbances
- Abnormal hair loss
- Drug fever
- Lupus-like syndrome
- Vasculitis
- Nephritis
- Hepatic disorders
- Taste disturbances
Pregnancy & Lactation
- May be given during pregnancy with caution
- Crosses placenta and excreted into breast milk
- May cause foetal or neonatal hypothyroidism and goitre
Precautions & Warnings
- Given with caution or not at all with tracheal obstruction
Overdose Effects
- May result in hypothyroidism and goitre
- Immediate withdrawal if blood dyscrasias occur
- Symptomatic and supportive treatment for overdose
Therapeutic Class
- Anti-thyroid drugs
Storage Conditions
- Keep below 30°C temperature
- Keep away from light & moisture
- Keep out of the reach of children