Akicin 500 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 48.14 (2 x 5: ৳ 481.40)

Medicine Details

Category Details
Generic Amikacin
Company Square pharmaceuticals plc
Also available as

Indications

Short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria, bacterial septicemia, respiratory tract infections, bone and joint infections, central nervous system infections, skin and soft tissue infections, intra-abdominal infections, burns, postoperative infections, complicated urinary tract infections, staphylococci infections

Pharmacology

Semi-synthetic aminoglycoside antibiotic, active against pseudomonas species, Escherichia coli, Proteus species, Providencia species, Klebsiella-Enterobacter species, Acinetobacter species, Citrobacter freundii, penicillinase and nonpenicillinase-producing Staphylococcus species

Dosage

Adult dose: 15 mg/kg/day in two equally-divided doses, Children's dose: 100 mg for accurate measurement, Neonates and premature children: loading dose of 10 mg/kg followed by 15 mg/kg/day, Elderly: dosage adjustment based on renal function, Life-threatening infections: dose may be increased to 500 mg every eight hours, Urinary tract infections: 7.5mg/kg/day, Impaired renal function: dose should be reduced and/or intervals between doses increased

Administration

Intramuscular or intravenous administration preferred for most infections, intraperitoneal use as an irrigant after recovery from anesthesia

Interaction

Concurrent administration with myorelaxants, other Aminoglycoside antibiotics, fast acting diuretics, Cephalosporins, and Polymixins should be avoided due to potential adverse effects

Contraindications

Hypersensitivity to Amikacin or any constituents of the injection

Side Effects

Tinnitus, vertigo, partial reversible or irreversible deafness, skin rash, drug fever, headache, paraesthesia, nausea, vomiting

Pregnancy & Lactation

Rapid crossing of placenta, potential risk of ototoxicity in the fetus, no information available regarding safety during breastfeeding

Precautions & Warnings

Patients should be well hydrated to minimize chemical irritation of the renal tubules, monitoring of renal function during treatment is important

Use in Special Populations

Safety and effectiveness in children or adolescents under 16 years not established

Overdose Effects

Peritoneal dialysis or haemodialysis in the event of overdose or toxic reaction

Therapeutic Class

Aminoglycosides

Storage Conditions

Keep below 30°C, away from light and moisture, keep out of the reach of children

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