Decafos 5 mg/ml (IM/IV Injection)
1 ml ampoule: ৳ 22.00 (2 x 5: ৳ 220.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Dexamethasone |
| Company | Techno drugs ltd |
Indications
- Allergic conditions in asthma
- Atopic dermatitis treatment
- Contact dermatitis control
- Perennial allergic rhinitis management
- Control of lupus erythematosus
- Bullous dermatitis herpetiformis treatment
- Primary adrenocortical insufficiency management
- Leukemias and lymphomas treatment
- Treatment of acute exacerbations of multiple sclerosis
- Inducing diuresis in nephrotic syndrome
- Berylliosis and tuberculosis treatment
- Adjunctive therapy for acute gouty arthritis
- Diagnostic testing of adrenocortical hyperfunction
- Treatment of neurologic involvement in trichinosis
- Tuberculous meningitis management
Pharmacology
- Synthetic glucocorticoid
- Inhibition of leukocyte migration
- Suppression of normal immune response
- Decrease in inflammation
Dosage & Administration
- Variability in adult and pediatric oral dosages
- Short dexamethasone suppression test
- Intravenous, intramuscular, and local injection options
- Use in systemic therapy for emergency situations
- Recommended doses for intra-articular and intrabursal injections
Interaction
- Potential interaction with diuretics and cardiac glycosides
- Effect on antidiabetics' efficacy
- Increased incidence of gastro-intestinal ulceration with NSAIDs
- Alteration of oral anticoagulants' needs
- Effectiveness decrease when used with liver enzyme inducing drugs
- Caution needed when co-administered with salicylates and antacids
- Possible impairment of gastrointestinal absorption when combined with certain antacids
Contraindications
- Gastric and duodenal ulcers
- Systemic and ophthalmic fungal infections
- Viral infections
- Glaucoma
- Hypersensitivity to corticosteroids
Side Effects
- Endocrine and metabolic disturbances
- Fluid and electrolyte disturbances
- Musculo-skeletal effects
- Gastro-intestinal effects
- Dermatological effects
- Central Nervous System effects
- Ophthalmic effects
- Immunosuppressive effects
Pregnancy & Lactation
- Pregnancy Category C
- Corticosteroids in breast milk
- Need for caution in breastfeeding
Precautions & Warnings
- Use of lowest possible dose
- Caution in cardio-renal patients
- Minimization of endocrine disturbances
- Caution in gastrointestinal conditions
- Special consideration for musculoskeletal health
- Attention to neuro-psychiatric effects
Use in Special Populations
- Titration to the lowest effective dose in pediatric patients
Overdose Effects
- Unlikelihood of overdosage
- Supportive and symptomatic therapy in case of overdosage
Storage Conditions
- Storage instructions for tablet and injection