Decason 5 mg/ml (IM/IV Injection)

1 ml ampoule: ৳ 25.00 (2 x 5: ৳ 250.00)

Medicine Details

Title and Categories

  • Dexamethasone Tablets
  • Pharmacology
  • Dosage & Administration
  • Interaction
  • Contraindications
  • Side Effects
  • Pregnancy & Lactation
  • Precautions & Warnings
  • Use in Special Populations
  • Overdose Effects
  • Storage Conditions

Indications

  • Asthma control
  • Allergic rhinitis treatment
  • Dermatitis management
  • Adrenocortical insufficiency
  • Renal diseases
  • Leukemias and lymphomas
  • Multiple sclerosis exacerbations
  • Temporal arteritis treatment
  • Ulcerative colitis management
  • Rheumatic disorders therapy
  • Tuberculous meningitis diagnosis

Mode of Action

Inhibits leukocyte migration and capillary permeability, suppresses immune response

Dosage & Administration

  • Oral dosages for adults and children
  • Short dexamethasone suppression test
  • Injection administration
  • Intravenous injection precautions and instructions
  • Infusion fluid compatibility
  • Systemic therapy dosage
  • Recommended local therapy doses

Interaction

  • Diuretics and cardiac glycosides interaction
  • Antidiabetics impact on glucose tolerance
  • NSAIDs and gastrointestinal ulceration risk
  • Alteration of oral anticoagulants' need
  • Effectiveness with liver enzyme inducing drugs
  • Caution with concomitant salicylates
  • Antacids interference with gastrointestinal absorption

Contraindications

  • Gastric and duodenal ulcers
  • Systemic and ophthalmic fungal infections
  • Viral infections contraindication
  • Glaucoma
  • Hypersensitivity to corticosteroids

Side Effects

  • Endocrine and metabolic disturbances
  • Fluid and electrolyte disturbances
  • Musculo-skeletal effects
  • Gastro-intestinal effects
  • Dermatological effects
  • Central Nervous System effects
  • Ophthalmic effects
  • Immunosuppressive effects

Pregnancy & Lactation

Category C for pregnancy, presence in breast milk

Precautions & Warnings

  • Use lowest possible dose
  • Caution in cardio-renal patients
  • Prevention of drug-induced secondary adrenocortical insufficiency
  • Gastrointestinal caution
  • Musculoskeletal considerations
  • Neuro-psychiatric observations

Use in Special Populations

Titration to lowest effective dose for pediatric patients

Overdose Effects

Unlikely, supportive and symptomatic therapy for treatment

Storage Conditions

  • Tablet storage
  • Injection storage

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