Cinamak 250 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 12.00 (2 x 5: ৳ 120.00)

Medicine Details

Category Details
Generic Amikacin
Company Techno drugs ltd
Also available as
Cinamak 500 mg injection

Title

  • Cinamak Injection

Categories

  • Medicine
  • Pharmaceutical

Description

  • Cinamak is a semi-synthetic aminoglycoside antibiotic indicated in the short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria.

Indications

  • Short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria
  • Effective in bacterial septicemia, serious respiratory tract infections, bone and joint infections, central nervous system infections, skin and soft tissue infections, intra-abdominal infections, burns, postoperative infections, complicated and recurrent urinary tract infections

Pharmacology

  • Active against pseudomonas species, Escherichia coli, Proteus species, Providencia species, Klebsiella-Enterobacter species, Acinetobacter species, Citrobacter freundii

Dosage

  • Adults and children: 15 mg/kg/day in two equally-divided doses
  • Neonates and premature children: An initial loading dose of 10 mg/kg followed by 15 mg/kg/day in two equally divided doses
  • Elderly: Dosage adjusted based on renal function
  • Life-threatening infections caused by Pseudomonas: Dose may be increased to 500 mg every eight hours

Administration

  • Intramuscular or intravenous administration
  • Intraperitoneal use as an irrigant after recovery from anesthesia in concentration of 0.25%

Interaction

  • Potentiation of myorelaxants' effects
  • Avoid concurrent use with other Aminoglycoside antibiotics, fast acting diuretics, Cephalosporins, or Polymixins

Contraindications

  • Hypersensitivity to Amikacin or any constituents of the injection

Side Effects

  • Tinnitus
  • Vertigo
  • Deafness
  • Skin rash
  • Drug fever
  • Headache
  • Nausea
  • Vomiting

Pregnancy & Lactation

  • Potential risk of ototoxicity in the fetus
  • No information available regarding safety during breastfeeding

Precautions & Warnings

  • Patients should be well hydrated to minimize renal irritation
  • Monitoring of renal function during treatment is important

Use in Special Populations

  • Safety and effectiveness not established in children or adolescents under 16 years

Overdose Effects

  • Peritoneal dialysis or haemodialysis aid in the removal of Cinamak from the blood

Therapeutic Class

  • Aminoglycosides

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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