Demax 5 mg/ml (IM/IV Injection)
1 ml ampoule: ৳ 15.00 (10's pack: ৳ 150.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Dexamethasone |
| Company | Medimet pharmaceuticals ltd |
| Also available as |
Indications
- Severe allergic conditions
- Collagen diseases treatment
- Dermatologic diseases control
- Management of endocrine disorders
- Gastrointestinal diseases treatment
- Hematologic disorders therapy
- Neoplastic diseases control
- Nervous system disorders treatment
- Ophthalmic diseases management
- Renal diseases treatment
- Respiratory diseases therapy
- Rheumatic disorders control
- Diagnostic testing of adrenocortical hyperfunction
- Trichinosis with neurologic or myocardial involvement treatment
- Tuberculous meningitis therapy
Pharmacology
Inhibits leukocyte migration and capillary permeability, suppresses normal immune response
Dosage & Administration
- Daily oral dosages for adults and children
- Short dexamethasone suppression test
- Intravenous, intramuscular, and local injection guidelines
- Recommended doses for systemic and emergency therapy
- Recommended doses for local therapy
Interaction
- Enhanced potassium loss with diuretics
- Impaired glucose tolerance with antidiabetics
- Increased gastrointestinal ulceration with NSAIDs
- Altered need for oral anticoagulants
- Effectiveness with liver enzyme inducing drugs
- Caution with concomitant use of salicylates and antacids
Contraindications
- Gastric and duodenal ulcers
- Systemic and ophthalmic fungal infections
- Viral infections
- Glaucoma
- Hypersensitivity to corticosteroids
Side Effects
- Endocrine and metabolic disturbances
- Fluid and electrolyte disturbances
- Musculo-skeletal effects
- Gastro-intestinal effects
- Dermatological effects
- Central Nervous System effects
- Ophthalmic effects
- Immunosuppressive effects
Pregnancy & Lactation
Pregnancy Category C, potential benefit justifies potential risk, glucocorticoids appear in breast milk
Precautions & Warnings
- Use lowest possible dose
- Use with caution in cardio-renal patients
- Minimize secondary adrenocortical insufficiency
- Caution in gastro-intestinal conditions
- Consideration for patients at risk of osteoporosis
- Neuro-psychiatric effects
Use in Special Populations
Pediatric patients should be titrated to the lowest effective dose
Overdose Effects
Treatment by supportive and symptomatic therapy
Storage Conditions
- Tablet storage guidelines
- Injection storage instructions