Dexamet 0.5 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Dexamethasone |
| Company | Rephco pharmaceuticals ltd |
| Also available as |
Indications
- Asthma control
- Allergic dermatitis treatment
- Rheumatoid arthritis control
- Gastrointestinal disease management
- Nervous system disorders
- Ophthalmic inflammation control
- Renal disease treatment
- Leukemias and lymphomas control
- Endocrine disorder management
- Respiratory disease management
- Rheumatic disorder treatment
- Neoplastic diseases control
- Hematologic disorder management
- Dermatologic disease treatment
- Diagnosis testing of adrenocortical hyperfunction
- Diuretic inducement
- Remission of proteinuria
- Symptomatic sarcoidosis management
- Chronic conditions therapy
Pharmacology
Dexamethasone is a synthetic glucocorticoid which decreases inflammation by inhibiting leukocyte migration and reversing increased capillary permeability. It suppresses the normal immune response.
Dosage & Administration
- Oral dosage for adults and children
- Dexamethasone suppression test
- Intravenous, intramuscular, and local injection guidance
- Systemic therapy dosage for adults, emergencies, and tapering off
- Local therapy dosage for intra-articular, intrabursal, and tendon sheath injections
- Infusion fluid options for dilution and administration
Interaction
- Diuretic and/or cardiac glycoside interaction
- Antidiabetic drug interaction
- Non-steroidal anti-inflammatory drug interaction
- Oral anticoagulant interaction
- Liver enzyme inducing drugs interaction
- Salicylate interaction
- Antacid interaction
Contraindications
- Gastric and duodenal ulcers
- Systemic and ophthalmic fungal infections
- Viral infections
- Glaucoma
- Hypersensitivity to corticosteroids
Side Effects
- Endocrine and metabolic disturbances
- Fluid and electrolyte disturbances
- Musculo-skeletal effects
- Gastro-intestinal effects
- Dermatological effects
- Central nervous system effects
- Ophthalmic effects
- Immunosuppressive effects
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if potential benefit justifies potential risk. Glucocorticoids appear in breast milk; caution advised for breastfeeding mothers taking high dosages.
Precautions & Warnings
- General precaution for lowest possible dose usage
- Cardio-renal caution
- Endocrine caution for secondary adrenocortical insufficiency
- Gastrointestinal caution for ulcerative conditions
- Musculoskeletal caution for osteoporosis risk
- Neuro-psychiatric caution for myopathy and psychiatric effects
Use in Special Populations
Pediatric patients should be titrated to the lowest effective dose to minimize potential growth effects.
Overdose Effects
Overdosage is unlikely; treatment is by supportive and symptomatic therapy.
Storage Conditions
- Tablet storage in cool, dry place protected from light & moisture
- Injection storage below 30°C, protected from light, non-freezing
Color Options
- White
- Off-White
Formulation
Tablet, Solution for injection
Ingredients
Dexamethasone, Lactose, Magnesium stearate, Microcrystalline cellulose, Sodium starch glycolate
Dimensions
Various tablet sizes and injection volumes
Usability Features
- Oral administration
- Injection administration
Technical Specifications
Potency, Purity, pH level, Sterility
Design Elements
Packaging design, Labeling
Material
Tablet: Cellulose-based, Injection: Glass vial, Rubber stopper
Product Name
Dexamethasone
Manufacturer
Multiple manufacturers
Dosage Forms
- Tablet
- Injection