Dexamethason 0.5 mg (Tablet)
Unit Price: ৳ 1.00 (100's pack: ৳ 100.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Dexamethasone |
| Company | Bristol pharmaceuticals ltd |
Indications
- Control of severe allergic conditions in asthma
- Treatment of atopic dermatitis
- Management of contact dermatitis
- Relief from drug hypersensitivity reactions
- Management of allergic rhinitis
- Treatment of serum sickness
- Treatment of collagen diseases like lupus erythematosus and rheumatoid arthritis
- Management of dermatologic diseases
- Treatment of endocrine disorders
- Control of gastrointestinal diseases
- Management of hematologic disorders
- Treatment of neoplastic diseases
- Management of nervous system conditions
- Treatment of ophthalmic diseases
- Induction of diuresis in renal diseases
- Relief from respiratory diseases
- Adjunctive therapy for rheumatic disorders
- Diagnostic testing of adrenocortical hyperfunction
- Treatment of trichinosis with neurologic involvement
- Management of tuberculous meningitis
- Migration of leukocytes inhibition
- Decrease in capillary permeability
- Suppression of immune response
Dosage & Administration
- Oral dosages in adult patients range from 1 mg to 10 mg
- Oral dosages in children range from 0.03 to 0.20 mg/kg body weight
- Short dexamethasone suppression test dosage at 1 mg
- Intravenous, intramuscular, and local injection administration
- Intravenous slow administration
- Deep intramuscular injection to prevent atrophy
- Intra-articular injections under aseptic conditions
- Dosage adjustment based on severity and patient response
Interaction
- Potential interactions with diuretics and cardiac glycosides
- Interactions with antidiabetics
- Interactions with non-steroidal anti-inflammatory drugs
- Effects on oral anti-coagulants
- Interactions with liver enzyme inducing drugs
- Concurrent use of salicylates and glucocorticoids
- Impact of antacids on glucocorticoid absorption
Contraindications
- Gastric and duodenal ulcers
- Systemic and ophthalmic fungal infections
- Viral infections like varicella and herpes genitalis
- Glaucoma
- Hypersensitivity to corticosteroids
Side Effects
- Cushing-like syndrome
- Fluid and electrolyte disturbances
- Musculo-skeletal effects like myopathy
- Gastro-intestinal effects like ulceration
- Dermatological effects like impaired wound healing
- Central Nervous System effects
- Ophthalmic effects like glaucoma
- Immunosuppressive effects
Pregnancy & Lactation
- Pregnancy Category C
- Use in pregnant women only if benefit outweighs risk
- Presence in breast milk
- Caution advised for breastfeeding mothers
Precautions & Warnings
- Use of lowest effective dose
- Caution in congestive heart failure patients
- Monitoring in patients with hypertension or renal insufficiency
- Minimization of endocrine disturbances
- Caution in gastrointestinal conditions
- Consideration for patients at risk of osteoporosis
- Acute myopathy risk with high doses
- Monitor neuro-psychiatric effects
Use in Special Populations
- Titration to lowest effective dose in pediatric patients
Overdose Effects
- Supportive and symptomatic therapy for overdosage
Storage Conditions
- Tablet storage in cool, dry place protected from light and moisture
- Injection storage below 30°C, protected from light, no freezing