Dexamin 5 mg/ml (IM/IV Injection)
1 ml ampoule: ৳ 18.05 (2 x 5: ৳ 180.50)
Medicine Details
| Category | Details |
|---|---|
| Generic | Dexamethasone |
| Company | Jayson pharmaceuticals ltd |
| Also available as |
Indications
- Control of severe or incapacitating allergic conditions
- Management of collagen disease
- Treatment of dermatologic diseases
- Management of endocrine disorders
- Treatment of gastrointestinal diseases
- Management of hematologic disorders
- Treatment of neoplastic diseases
- Management of nervous system conditions
- Treatment of ophthalmic diseases
- Management of renal diseases
- Treatment of respiratory diseases
- Management of rheumatic disorders
- Diagnostic testing of adrenocortical hyperfunction
Pharmacology
- Synthetic glucocorticoid
- Inhibition of leukocyte migration
- Reversal of capillary permeability
- Suppression of normal immune response
Dosage & Administration
- Tablet Daily Dosage: 1 mg to 10 mg for adults
- Tablet Dosage for Children: 0.03 mg/kg to 0.20 mg/kg body weight
- Short Dexamethasone Suppression Test: 1 mg dose at 11 p.m.
- Injection Administration: Intravenous (IV), intramuscular (IM) or local injection
- Intravenous Injection: Given slowly over several minutes
- Intramuscular Administration: Deep intramuscular injection
- Intra-articular Injection: Under strictly aseptic conditions
- Injections Potency Maintenance: At least 24 hours when diluted with infusion fluids
Interaction
- Enhanced potassium loss with diuretics and/or cardiac glycosides
- Impaired glucose tolerance with antidiabetics
- Increased incidence and severity of gastrointestinal ulceration with non-steroidal anti-inflammatory drugs
- Alteration of need for oral anticoagulants
- Reduced effectiveness with liver enzyme inducing drugs
- Risk of salicylate intoxication when used concomitantly with long-term therapy
- Impaired gastrointestinal absorption with certain antacids
Contraindications
- Gastric and duodenal ulcers
- Systemic and ophthalmic fungal infections
- Viral infections
- Glaucoma
- Hypersensitivity to corticosteroids
Side Effects
- Cushing-like syndrome
- Fluid and electrolyte disturbances
- Musculo-skeletal effects
- Gastro-intestinal effects
- Dermatological effects
- Central Nervous System effects
- Ophthalmic effects
- Immunosuppressive effects
Pregnancy & Lactation
- Pregnancy Category: C
- Breastfeeding Advice: Avoid in high dosages
Precautions & Warnings
- Use the lowest possible dose
- Caution in cardio-renal patients
- Minimize secondary adrenocortical insufficiency risk
- Use with caution in gastrointestinal conditions
- Consideration for patients at increased osteoporosis risk
- Monitor for acute myopathy with high doses
Use in Special Populations
Titration to lowest effective dose for pediatric patients
Overdose Effects
Supportive and symptomatic therapy
Storage Conditions
- Tablet: Cool & dry place, protected from light & moisture
- Injection: Below 30°C, protected from light, do not freeze