Cinamak 500 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 20.98 (2 x 5: ৳ 209.80)

Medicine Details

Category Details
Generic Amikacin
Company Techno drugs ltd
Also available as

Indications

  • Short-term treatment of serious infections
  • Effective in bacterial septicemia
  • Treats serious infections of the respiratory tract, bones and joints, central nervous system, skin, and soft tissue
  • Effective in intra-abdominal infections and burns
  • Effective in infections caused by gentamicin and/or tobramycin-resistant strains
  • Effective in staphylococci infections

Pharmacology

  • Semi-synthetic aminoglycoside antibiotic
  • Active against pseudomonas, Escherichia coli, Proteus, Providencia, Klebsiella, Acinetobacter, and Citrobacter species
  • Active against penicillinase and nonpenicillinase-producing Staphylococcus species

Dosage

  • Recommended dosage for adults and children
  • Recommended dosage for neonates and premature children
  • Dosage adjustment for the elderly
  • Dosage for life-threatening infections and those caused by Pseudomonas
  • Dosage for urinary tract infections
  • Dosage adjustment for impaired renal function

Administration

  • Intramuscular or intravenous administration for most infections
  • Intravenous route for life-threatening infections
  • Intraperitoneal use as an irrigant

Interaction

  • Potentiation of myorelaxants effects
  • Avoidance of concurrent administration with other Aminoglycoside antibiotics
  • Increased risk of ototoxicity with fast-acting diuretics
  • Increased risk of nephrotoxicity with Cephalosporins or Polymixins

Contraindications

  • Contraindicated in patients with known hypersensitivity to Amikacin

Side Effects

  • Reported adverse effects: tinnitus, vertigo, reversible or irreversible deafness, skin rash, drug fever, headache, paraesthesia, nausea, vomiting

Pregnancy & Lactation

  • Rapid crossing of the placenta into the fetal circulation and amniotic fluid
  • Potential risk of ototoxicity in the fetus
  • No information about safety during breastfeeding

Precautions & Warnings

  • Hydration to minimize chemical irritation of the renal tubules
  • Monitoring of renal function during treatment with aminoglycosides

Use in Special Populations

  • Unestablished safety and effectiveness in children or adolescents under 16 years

Overdose Effects

  • Peritoneal dialysis or haemodialysis aid in the removal of Cinamak from the blood

Therapeutic Class

  • Aminoglycosides

Storage Conditions

  • Storage below 30°C temperature
  • Storage away from light and moisture
  • Keep out of the reach of children

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