Dextason 0.5 mg (Tablet)
Unit Price: ৳ 0.60 (10 x 10: ৳ 60.00)
Strip Price: ৳ 6.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Dexamethasone |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Indications
- Severe allergic conditions in asthma
- Atopic dermatitis control
- Contact dermatitis control
- Drug hypersensitivity reactions control
- Perennial allergic rhinitis control
- Serum sickness control
- Lupus erythematosus control
- Bullous dermatitis herpetiformis control
- Exfoliative erythroderma control
- Mycosis fungoides control
- Pemphigus control
- Severe erythema multiforme control
- Primary adrenocortical insufficiency treatment
- Congenital adrenal hyperplasia treatment
- Hypercalcemia associated with cancer treatment
- Nonsuppurative thyroiditis treatment
- Berylliosis control
- Fulminating or disseminated pulmonary tuberculosis control
- Idiopathic eosinophilic pneumonias treatment
- Symptomatic sarcoidosis treatment
- Acute exacerbations of multiple sclerosis treatment
Pharmacology
- Synthetic glucocorticoid
- Inflammation reduction
- Leukocyte migration inhibition
- Capillary permeability reversal
- Immune response suppression
Dosage & Administration
- Daily Oral Dosage (Adults): 1-10 mg
- Daily Oral Dosage (Children): 0.03-0.20 mg/kg body weight
- Dexamethasone Suppression Test Dosage: 1 mg or 0.5 mg every 6 hours
- Intravenous Injection Dosage: Massive doses given slowly
- Intramuscular Injection Dosage: Deep intramuscular injection
- Local Therapy Dosage: 2-4 mg in large joints, 0.8-1 mg in small joints
Interaction
- Enhanced potassium loss with diuretics and/or cardiac glycosides
- Impaired glucose tolerance with antidiabetics
- Increased gastro-intestinal ulceration incidence/severity with non-steroidal anti-inflammatory drugs
- Altered need for oral anti-coagulants
- Less effectiveness with liver enzyme inducing drugs
Contraindications
- Gastric and duodenal ulcers
- Systemic and ophthalmic fungal infections
- Viral infections (e.g. varicella and herpes genitalis infections)
- Glaucoma
- Hypersensitivity to corticosteroids
Side Effects
- Cushing-like syndrome
- Hirsutism
- Menstrual irregularities
- Osteoporosis
- Aseptic necrosis of femoral and humeral heads
- Gastric and duodenal ulceration
- Skin atrophy
- Psychic disturbances
- Glaucoma
- Increased susceptibility to infections
Pregnancy & Lactation
- Pregnancy Category C
- Potential presence in breast milk
Precautions & Warnings
- Use lowest possible dose
- Caution in cardio-renal conditions
- Minimize drug-induced secondary adrenocortical insufficiency
- Caution in gastrointestinal conditions
- Consideration for patients at risk of osteoporosis
- Be aware of acute myopathy potential
Use in Special Populations
Titration to lowest effective dose for pediatric patients
Overdose Effects
Treatment by supportive and symptomatic therapy
Storage Conditions
- Tablet: Cool, dry place; protected from light and moisture
- Injection: Below 30°C; protected from light