Odeson 4 mg/ml (IM/IV Injection)
1 ml ampoule: ৳ 15.00 (2 x 5: ৳ 150.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Dexamethasone |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Control of severe or incapacitating allergic conditions
- Treatment of collagen diseases like lupus erythematosus and rheumatoid arthritis
- Management of dermatologic diseases including bullous dermatitis herpetiformis and mycosis fungoides
- Treatment of endocrine disorders such as adrenal insufficiency and hypercalcemia
- Control of gastrointestinal diseases like ulcerative colitis
- Management of hematologic disorders such as autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura
- Treatment of neoplastic diseases like leukemias and lymphomas
- Management of nervous system conditions such as acute exacerbations of multiple sclerosis
- Treatment of ophthalmic diseases like uveitis and ocular inflammatory conditions
- Induction of diuresis or remission of proteinuria in renal diseases
- Management of respiratory diseases including pulmonary tuberculosis and sarcoidosis
- Adjunctive therapy for rheumatic disorders like rheumatoid arthritis and psoriatic arthritis
- Diagnostic testing of adrenocortical hyperfunction
- Treatment of trichinosis and tuberculous meningitis
- Pharmacology: Decreases inflammation, suppresses normal immune response
Dosage & Administration
- Oral dosages for adult patients: 1 mg to 10 mg daily
- Oral dosages for children: 0.03-0.20 mg/kg body weight
- Variation in dosages based on individual response
- Use of dexamethasone suppression test
- Intravenous, intramuscular, and local injection administration
- Dosage adjustment for systemic therapy in adults
- Recommended doses for intra-articular, intrabursal, and tendon sheath injections
Interaction
- Diuretics and/or cardiac glycosides
- Antidiabetics
- Non-steroidal anti-inflammatory drugs
- Oral anti-coagulants
- Less effectiveness with liver enzyme inducing drugs
- Concomitant use with salicylates
- Potential interaction with antacids
Contraindications
- Gastric and duodenal ulcers
- Systemic and ophthalmic fungal infections
- Viral infections such as varicella and herpes genitalis infections
- Glaucoma
- Hypersensitivity to corticosteroids
Side Effects
- Endocrine and metabolic disturbances
- Fluid and electrolyte disturbances
- Musculo-skeletal effects
- Gastro-intestinal effects
- Dermatological effects
- Central Nervous System effects
- Ophthalmic effects
- Immunosuppressive effects
Pregnancy & Lactation
- Pregnancy Category C
- Use during pregnancy only if potential benefit justifies potential risk
- Presence in breast milk
- Advice against breastfeeding for mothers taking high dosages
Precautions & Warnings
- Use of lowest possible dose
- Caution in patients with congestive heart failure, hypertension, or renal insufficiency
- Minimization of drug-induced secondary adrenocortical insufficiency
- Use with caution in certain gastrointestinal and musculoskeletal conditions
- Caution regarding neuro-psychiatric effects
Use in Special Populations
- Titration to the lowest effective dose for pediatric patients
Overdose Effects
- Supportive and symptomatic therapy
Storage Conditions
- Tablet: Store in a cool & dry place, protected from light & moisture
- Injection: Store below 30°C, protected from light. Do not freeze