Roxadex 5 mg/ml (IM/IV Injection)

1 ml ampoule: ৳ 29.02 (2 x 5: ৳ 290.20)

Medicine Details

Indications

  • Allergic states
  • Collagen disease
  • Dermatologic diseases
  • Endocrine disorders
  • Gastrointestinal diseases
  • Hematologic disorders
  • Neoplastic diseases
  • Nervous system
  • Ophthalmic diseases
  • Renal diseases
  • Respiratory diseases
  • Rheumatic disorders
  • Miscellaneous

Pharmacology

Synthetic glucocorticoid, decreases inflammation, inhibits migration of leukocytes, suppresses normal immune response

Dosage & Administration

  • Tablet:
    • Adult dosage: 1-10 mg daily
    • Children dosage: 0.03-0.20 mg/kg body weight
  • Injection:
    • Can be given intravenously, intramuscularly, or as local injection
    • Dosage depends on the severity of the condition and the patient's response

Interaction

  • Diuretics and/or cardiac glycosides
  • Antidiabetics
  • Non-steroidal anti-inflammatory drugs
  • Oral anti-coagulants
  • Liver enzyme inducing drugs
  • Salicylates
  • Antacids

Contraindications

  • Gastric and duodenal ulcers
  • Systemic and ophthalmic fungal infections
  • Viral infections
  • Glaucoma
  • Hypersensitivity to corticosteroids

Side Effects

  • Endocrine and metabolic disturbances
  • Fluid and electrolyte disturbances
  • Musculo-skeletal effects
  • Gastro-intestinal effects
  • Dermatological effects
  • Central Nervous System effects
  • Ophthalmic effects
  • Immunosuppressive effects

Pregnancy & Lactation

Pregnancy Category C, should be used only if benefit justifies potential risk to fetus, appear in breast milk

Precautions & Warnings

  • Use lowest possible dose
  • Cardio-renal caution
  • Gradual reduction of dosage
  • Use with caution in gastrointestinal conditions
  • Consider osteoporosis risk
  • Neuro-psychiatric considerations

Use in Special Populations

To minimize potential growth effects, pediatric patients should be titrated to the lowest effective dose

Overdose Effects

Treatment is by supportive and symptomatic therapy

Storage Conditions

  • Tablet: Cool & dry place, protected from light & moisture
  • Injection: Below 30°C, protected from light, do not freeze, keep out of reach of children

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