Cortef 100 mg/2 ml (IM/IV Injection)
100 mg vial: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Hydrocortisone |
| Company | Aristopharma ltd |
Title
- Cortef Hydrocortisone Tablets
Categories
- Medicine
- Pharmaceuticals
- Healthcare
Description
- A medication used in various conditions related to adrenocortical insufficiency, shock, hypercalcemia, allergic conditions, rheumatic disorders, dermatologic diseases, inflammatory diseases, and more.
- Inhibits prostaglandin synthesis, reduces vasoactive agents, and controls the rate of protein synthesis.
- Available in tablet and injection forms with varying dosage recommendations.
- Interacts with drugs that induce hepatic enzymes or inhibit corticosteroid metabolism.
- Contraindicated in severe systemic fungal infections and known hypersensitivity to any component of the product.
- Common side effects include cardiac arrhythmia, fluid retention, weight gain, mood swings, insomnia, and acne.
- Should be prescribed in pregnancy and lactation only if absolutely required.
- Precautions include using with caution in patients with a history of peptic ulceration, congestive heart failure, hypertension, glaucoma, diabetes, and epilepsy.
- Belongs to the therapeutic class of glucocorticoids.
- Storage conditions require keeping the product below 30°C temperature, away from light and moisture, and out of the reach of children.
Indications
- Primary or secondary adrenocortical insufficiency
- Acute adrenocortical insufficiency
- Shock unresponsive to conventional therapy
- Congenital adrenal hyperplasia
- Hypercalcemia associated with cancer
- Nonsuppurative thyroiditis
- Rheumatic Disorders
- Severe dermatologic diseases
- Severe allergic conditions
- Ophthalmic Diseases
- Gastrointestinal Diseases
- Pulmonary tuberculosis
- Loeffler's syndrome
- Aspiration pneumonitis
- Hematologic Disorders
- Neoplastic Diseases
- Edematous States
- Acute exacerbations of multiple sclerosis
Pharmacology
- Inhibits prostaglandin synthesis
- Reduces vasoactive agents released during inflammation
- Controls the rate of protein synthesis
Dosage & Administration
- Initial dosage may vary from 20 mg to 240 mg of hydrocortisone per day
- Lower doses may suffice in less severe situations, while higher doses may be required in selected patients
- Dosage requirements are variable and must be individualized based on the disease under treatment and the patient's response
- Injection dosage varies for adults and children
Interaction
- Drugs that induce hepatic enzymes may increase the clearance of corticosteroids
- Drugs such as Troleandomycin and Ketoconazole may inhibit the metabolism of corticosteroids
Contraindications
- Severe systemic fungal infections
- Known hypersensitivity to any component of the product
Side Effects
- Cardiac arrhythmia
- Esophageal candidiasis
- Menstrual irregularity
- Decreased carbohydrate & glucose tolerance
- Fluid retention
- Increased appetite
- Weight gain
- Mood swings
- Depression
- Insomnia
- Acne
Pregnancy & Lactation
- Should be prescribed only if absolutely required
Precautions & Warnings
- Use with caution in patients with a history of peptic ulceration
- Caution in patients with congestive heart failure, hypertension, glaucoma, diabetic mellitus, and epilepsy
Therapeutic Class
- Glucocorticoids
Storage Conditions
- Keep below 30°C temperature
- Keep away from light and moisture
- Keep out of the reach of children