Cotson 10 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Hydrocortisone |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Primary or secondary adrenocortical insufficiency
- Acute adrenocortical insufficiency
- Shock unresponsive to conventional therapy
- Congenital adrenal hyperplasia
- Hypercalcemia associated with cancer
- Nonsuppurative thyroiditis
- Rheumatic Disorders
- Dermatologic Diseases
- Control of severe or incapacitating allergic conditions
- Ophthalmic Diseases
- Gastrointestinal Diseases
- Fulminating or disseminated pulmonary tuberculosis
- Loeffler's syndrome
- Aspiration pneumonitis
- Hematologic Disorders
- Neoplastic Diseases
- Edematous States
- Acute exacerbations of multiple sclerosis
Pharmacology
Hydrocortisone inhibits prostaglandin synthesis, reduces vasoactive agents during inflammation, and controls the rate of protein synthesis.
Dosage & Administration
- Initial dosage may vary from 20 mg to 240 mg per day
- Dosage requirements are variable and must be individualized based on the disease under treatment
- Injection dosage for adults and children is specified
Interaction
Drugs that induce hepatic enzymes may increase the clearance of corticosteroids. Drugs like Troleandomycin and Ketoconazole may inhibit the metabolism of corticosteroids.
Contraindications
Contraindicated in severe systemic fungal infections and patients with known hypersensitivity to any component of the product.
Side Effects
- Generally well-tolerated except in prolonged high doses
- May cause cardiac arrhythmia, esophageal candidiasis, menstrual irregularity, decreased carbohydrate & glucose tolerance, fluid retention, increased appetite, weight gain, euphoria, mood swings, depression, insomnia, acne etc.
Pregnancy & Lactation
Should be prescribed in pregnancy and lactation only if absolutely required.
Precautions & Warnings
Use with caution in patients with a history of peptic ulceration, congestive heart failure, hypertension, glaucoma, diabetic mellitus, and epilepsy.
Therapeutic Class
Glucocorticoids
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.