Cortan 5 mg (Tablet)
Unit Price: ৳ 1.72 (15 x 14: ৳ 361.20)
Strip Price: ৳ 24.08
Medicine Details
| Category | Details |
|---|---|
| Generic | Prednisolone |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Psoriatic arthritis
- Rheumatoid arthritis
- Juvenile rheumatoid arthritis
- Ankylosing spondylitis
- Acute and subacute bursitis
- Acute nonspecific tenosynovitis
- Acute gouty arthritis
- Post-traumatic osteoarthritis
- Primary or secondary adrenocortical insufficiency
- Congenital adrenal hyperplasia
- Nonsuppurative thyroiditis
- Hypercalcemia associated with cancer
- Pemphigus
- Bullous dermatitis herpetiformis
- Severe erythema multiforme
- Exfoliative dermatitis
- Mycosis fungoides
- Severe psoriasis
- Seasonal or perennial allergic rhinitis
- Bronchial asthma
- Contact dermatitis
- Atopic dermatitis
- Symptomatic sarcoidosis
- Berylliosis
- Fulminating aspiration pneumonitis
- Idiopathic thrombocytopenic purpura
- Secondary thrombocytopenia
- Acquired (autoimmune) hemolytic anemia
- Erythroblastopenia (RBC anemia)
- To induce diuresis in nephrotic syndrome
- Ulcerative colitis
- Regional enteritis
Pharmacology
- Synthetic adrenocortical drug
- Glucocorticoid properties
- Inhibition of Phospholipase A2 enzyme
- Rapid and well absorption from gastrointestinal tract
- 70-90% protein-bound in plasma
- Metabolism mainly in the liver
- Excretion in the urine
Dosage & Administration
- Adult:
- Nephrotic Syndrome: 2 mg/kg/day (maximum 80 mg/day)
- Anti-inflammatory: 5 to 60 mg per day
- Acute Asthma: 40-60 mg/day in single or divided doses
- Allergic Conditions: Day-wise dosage variation
- Pediatric:
- Asthma: Dosage based on age
- Anti-inflammatory: 0.05 to 2 mg/kg/day
- Immunosuppression: 0.05 to 2 mg/kg/day
Interaction
- Reduced efficacy by Aminoglutethimide, Antacids, Barbiturates, Carbamazepine, Griseofulvin, Mitotane, Phenylbutazone, Phenytoin, Primidone and Rifampin
- Reduction of potassium levels in the blood
- Potential cardiac arrhythmias with Digitalis
- Careful immunization required
Contraindications
- Systemic infections without specific anti-infective therapy
- Hypersensitivity to any ingredient
- Ocular herpes simplex
Side Effects
- Increased appetite
- Indigestion
- Nervousness or restlessness
- Changes in skin color
- Dizziness or lightheadedness
- Facial flushing
- Hiccups
- Increased sweating
- Sensation of spinning
Pregnancy & Lactation
Not recommended during pregnancy, caution needed during lactation
Precautions & Warnings
- Diabetes
- Hypertension
- Psychological disturbances
- Osteoporosis
- Post-menopausal women
- Chronic nephritis
- Possible Cushing's habitus
- Hyperglycemia
- Muscular weakness
- Increased susceptibility to infection
- Delayed wound healing
- Psychiatric disturbances
Overdose Effects
Adverse effects after prolonged use, gradual dose reduction recommended
Therapeutic Class
Glucocorticoids
Storage Conditions
Cool, dry place, protected from light, keep out of reach of children