Cortisol 5 mg/5 ml (Oral Solution)

50 ml bottle: ৳ 65.00

Medicine Details

Indications

  • Treatment of rheumatic disorders like psoriatic arthritis, rheumatoid arthritis, and ankylosing spondylitis
  • Management of endocrine disorders including adrenal insufficiency and nonsuppurative thyroiditis
  • Therapy for dermatologic diseases such as pemphigus and severe psoriasis
  • Management of allergic states like seasonal or perennial allergic rhinitis and bronchial asthma
  • Treatment of respiratory diseases like sarcoidosis and aspiration pneumonitis
  • Management of edematous states like nephrotic syndrome
  • Therapy for gastrointestinal diseases like ulcerative colitis and regional enteritis
  • Treatment of hematologic disorders including idiopathic thrombocytopenic purpura and autoimmune hemolytic anemia

Pharmacology

  • Synthetic adrenocortical drug with predominantly glucocorticoid properties
  • Inhibits the action of Phospholipase A2 enzyme responsible for production of inflammatory mediators
  • Rapid and well-absorbed from the gastrointestinal tract
  • Metabolized mainly in the liver and excreted in the urine

Dosage & Administration

  • Adult dosage for nephrotic syndrome, anti-inflammatory, and acute asthma
  • Pediatric dosage for asthma, anti-inflammatory, and immunosuppression

Interaction

  • Reduction of efficacy by Aminoglutethimide, Antacids, Barbiturates, Carbamazepine, and other medications
  • Reduced potassium levels in the blood by Cortisol
  • Potential cardiac arrhythmias with hypokalemia and Digitalis use
  • Careful administration of immunizations

Contraindications

  • Systemic infections without specific anti-infective therapy
  • Hypersensitivity to any ingredient
  • Ocular herpes simplex

Side Effects

  • Increased appetite
  • Indigestion
  • Nervousness or restlessness
  • Changes in skin color
  • Dizziness or lightheadedness
  • Flushing of face or cheeks
  • Hiccups
  • Increased sweating
  • Sensation of spinning

Pregnancy & Lactation

  • Not recommended for use during pregnancy unless essential
  • Potential presence in breast milk

Precautions & Warnings

  • Precaution in diabetes, hypertension, and psychological disturbances
  • Risk of Cushing's habitus, hyperglycemia, and muscular weakness with long-term use

Overdose Effects

  • Adverse effects develop after prolonged use of excessive doses
  • Symptomatic treatment
  • Gradual reduction of dose

Therapeutic Class

  • Glucocorticoids

Storage Conditions

  • Store in cool and dry place
  • Protect from light
  • Keep out of reach of children

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