Deltacort 5 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Prednisolone |
| Company | Desh pharmaceuticals ltd |
Indications
- Rheumatic Disorders
- Endocrine Disorders
- Dermatologic Diseases
- Allergic States
- Respiratory Diseases
- Hematologic Disorders
- Edematous States
- Gastrointestinal Diseases
Pharmacology
Prednisolone is a synthetic adrenocortical drug with predominantly glucocorticoid properties. It inhibits the action of the Phospholipase A2 enzyme responsible for the production of inflammatory mediators. It is rapidly absorbed from the gastrointestinal tract, protein-bound in the plasma, metabolized mainly in the liver, and excreted in the urine.
Dosage & Administration
- Adult:
- Nephrotic Syndrome: Initial dose: 2 mg/kg/day (maximum 80 mg/day) in divided doses. Maintenance dose: 0.5 to 1 mg/kg/dose. Anti-inflammatory: 5 to 60 mg per day.
- Acute Asthma: 40-60 mg/day PO in single daily dose or divided q12 hr for 3-10 days.
- Allergic Conditions:
- Day-wise tapering dosage for 6 days
- Pediatric:
- Asthma: Dosage varies by age group. Anti-inflammatory: 0.05 to 2 mg/kg/day. Immunosuppression: 0.05 to 2 mg/kg/day.
Interaction
Reduction of efficacy by various drugs such as Aminoglutethimide, Antacids, Barbiturates, Carbamazepine, etc. Reduction of potassium levels by Deltacort. Caution with immunization.
Contraindications
Systemic infections, hypersensitivity to any ingredient, ocular herpes simplex.
Side Effects
- Increased appetite
- Indigestion
- Nervousness or restlessness
- Changes in skin color
- Dizziness or lightheadedness
- Increased sweating
- Sensation of spinning
Pregnancy & Lactation
Not recommended during pregnancy unless essential. Caution with breastfeeding due to corticosteroids excretion in breast milk.
Precautions & Warnings
Diabetes, hypertension, Psychological disturbances, osteoporosis, pregnancy, chronic nephritis. Long-term use can cause Cushing's habitus, hyperglycemia, muscular weakness, increased susceptibility to infection, etc.
Overdose Effects
Adverse effects develop after prolonged use of excessive doses. Treatment is symptomatic.
Therapeutic Class
Glucocorticoids
Storage Conditions
Store in a cool, dry place, protected from light. Keep out of the reach of children.