Psudonil 250 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 30.10 (1 x 5: ৳ 150.50)

Medicine Details

Indications

  • Short-term treatment of serious infections
  • Treatment of bacterial septicemia
  • Treatment of respiratory tract infections
  • Treatment of bone and joint infections
  • Treatment of central nervous system infections
  • Treatment of skin and soft tissue infections
  • Treatment of intra-abdominal infections
  • Treatment of burns and postoperative infections
  • Effective against gentamicin and tobramycin-resistant strains
  • Effective in staphylococci infections

Pharmacology

  • Semi-synthetic aminoglycoside antibiotic
  • Active against various bacteria species
  • Active against penicillinase and nonpenicillinase-producing Staphylococcus species
  • Effective in vitro against resistant strains

Dosage

  • Dosage for adults and children
  • Dosage for neonates and premature children
  • Dosage for elderly
  • Dosage for life-threatening infections
  • Dosage for urinary tract infections
  • Dosage for impaired renal function

Administration

  • Intramuscular or intravenous administration for most infections
  • Intravenous route for life-threatening infections
  • Intraperitoneal use as an irrigant

Interaction

  • Potentiation of effects with myorelaxants
  • Avoidance of combination with other aminoglycoside antibiotics
  • Increased risk of ototoxicity with fast-acting diuretics
  • Increased risk of nephrotoxicity with Cephalosporins or Polymixins

Contraindications

  • Contraindicated in patients with known hypersensitivity

Side Effects

  • Adverse effects such as tinnitus, vertigo, reversible or irreversible deafness, skin rash, drug fever, headache, paraesthesia, nausea, and vomiting

Pregnancy & Lactation

  • Potential risk of ototoxicity in the fetus
  • No safety information during breastfeeding

Precautions & Warnings

  • Importance of hydration to minimize renal tubule irritation
  • Need for monitoring renal function during treatment

Use in Special Populations

  • Lack of established safety and effectiveness for children or adolescents under 16 years

Overdose Effects

  • Peritoneal dialysis or haemodialysis in case of overdose or toxic reaction

Therapeutic Class

  • Belongs to the Aminoglycosides class

Storage Conditions

  • Recommended storage below 30°C, away from light and moisture

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