Edruson 5 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Prednisolone |
| Company | Edruc limited |
Title
- Edruson Tablet
Categories
- Medicine
- Pharmaceutical
Description
- Prednisolone is a synthetic adrenocortical drug with predominantly glucocorticoid properties.
- It is used to treat various conditions such as Rheumatic Disorders, Endocrine Disorders, Dermatologic Diseases, Allergic States, Respiratory Diseases, Hematologic Disorders, Edematous States, Gastrointestinal Diseases, and more.
DosageRange
- 5 to 60 mg per day for adults in divided doses
- 10 to 40 mg orally every 12 hours for pediatric use
Pharmacology
Prednisolone directly inhibits the action of the Phospholipase A2 enzyme which is responsible for the production of different inflammatory mediators. It is rapidly and well absorbed from the gastrointestinal tract following oral administration.
Interaction
- Reduced efficacy if taken with Aminoglutethimide, Antacids, Barbiturates, Carbamazepine, Griseofulvin, Mitotane, Phenylbutazone, Phenytoin, Primidone, or Rifampin
- Digitalis can cause Cardiac arrhythmias if hypokalemia occurs
Contraindications
- Systemic infections unless specific anti-infective therapy is employed
- Hypersensitivity to any ingredient
- Ocular herpes simplex because of possible perforation
SideEffects
- Increased appetite
- Indigestion
- Nervousness or restlessness
- Darkening or lightening of skin color
- Dizziness or lightheadedness
- Flushing of face or cheeks
- Hiccups
- Increased sweating
- Sensation of spinning
PregnancyAndLactation
Not recommended for use during pregnancy unless considered essential by a doctor. Corticosteroids appear in breast milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other unwanted effects.
PrecautionsAndWarnings
- Precaution has to be taken in diabetes, hypertension, Psychological disturbances, osteoporosis, post-menopausal women, pregnancy, and in chronic nephritis
- Long-term use can cause Cushing's habitus, hyperglycemia, muscular weakness, increased susceptibility to infection, delayed wound healing, and psychiatric disturbances
OverdoseEffects
Adverse effects related to prednisone normally develop only after prolonged use of doses in excess of the normal physiological requirement. Treatment is symptomatic and where possible the prednisone dose should be reduced gradually.
TherapeuticClass
Glucocorticoids
StorageConditions
Store in a cool and dry place, protected from light. Keep out of the reach of children