G-Prednisolone 5 mg (Tablet)

Unit Price: ৳ 1.72 (10 x 10: ৳ 172.00)
Strip Price: ৳ 17.20

Medicine Details

Category Details
Generic Prednisolone
Company Gonoshasthaya pharma ltd

Indications

  • Rheumatic Disorders
  • Psoriatic arthritis
  • Rheumatoid arthritis
  • Juvenile rheumatoid arthritis
  • Ankylosing spondylitis
  • Acute and subacute bursitis
  • Acute nonspecific tenosynovitis
  • Acute gouty arthritis
  • Post-traumatic osteoarthritis
  • Endocrine Disorders
  • Primary or secondary adrenocortical insufficiency
  • Congenital adrenal hyperplasia
  • Nonsuppurative thyroiditis
  • Hypercalcemia associated with cancer
  • Dermatologic Diseases
  • Pemphigus
  • Bullous dermatitis herpetiformis
  • Severe erythema multiforme
  • Exfoliative dermatitis
  • Mycosis fungoides
  • Severe psoriasis
  • Allergic States
  • Seasonal or perennial allergic rhinitis
  • Bronchial asthma
  • Contact dermatitis
  • Atopic dermatitis
  • Respiratory Diseases
  • Symptomatic sarcoidosis
  • Berylliosis
  • Fulminating aspiration pneumonitis
  • Hematologic Disorders
  • Idiopathic thrombocytopenic purpura
  • Secondary thrombocytopenia
  • Acquired (autoimmune) hemolytic anemia
  • Erythroblastopenia (RBC anemia)
  • Edematous States
  • Diuresis
  • Remission of proteinuria
  • Nephrotic syndrome
  • Ulcerative colitis
  • Regional enteritis

Pharmacology

  • Synthetic adrenocortical drug
  • Glucocorticoid properties
  • Inhibition of Phospholipase A2 enzyme
  • Inhibition of production of inflammatory mediators
  • Rapid and well absorption from the GI tract
  • 70-90% protein-bound in the plasma
  • Metabolized mainly in the liver
  • Eliminated in the urine

Dosage & Administration

  • Dosage for Nephrotic Syndrome
  • Maintenance dose
  • Anti-inflammatory dose for adults
  • Acute Asthma dosage
  • Allergic Conditions dosage for adults
  • Asthma dosage for pediatric
  • Maintenance dose for pediatric
  • Immunosuppression dose for pediatric

Interaction

  • Reduced efficacy by Aminoglutethimide
  • Reduced efficacy by Antacids
  • Reduced efficacy by Barbiturates
  • Reduced efficacy by Carbamazepine
  • Reduced efficacy by Griseofulvin
  • Reduced efficacy by Mitotane
  • Reduced efficacy by Phenylbutazone
  • Reduced efficacy by Phenytoin
  • Reduced efficacy by Primidone
  • Reduced efficacy by Rifampin
  • Reduction of potassium level in the blood
  • Potential cardiac arrhythmias with Digitalis
  • Precautions for immunization

Contraindications

  • Systemic infections
  • Hypersensitivity to any ingredient
  • Ocular herpes simplex

Side Effects

  • Increased appetite
  • Indigestion
  • Nervousness or restlessness
  • Darkening or lightening of skin color
  • Dizziness or lightheadedness
  • Flushing of face or cheeks
  • Hiccups
  • Increased sweating
  • Sensation of spinning

Pregnancy & Lactation

  • Not recommended during pregnancy
  • Considered essential only with doctor's approval
  • Corticosteroids present in breast milk

Precautions & Warnings

  • Precaution in diabetes
  • Precaution in hypertension
  • Precaution in Psychological disturbances
  • Precaution in osteoporosis
  • Precaution in post-menopausal women
  • Precaution in chronic nephritis
  • Potential long-term effects

Overdose Effects

  • Adverse effects
  • Symptomatic treatment
  • Gradual reduction of prednisone dose

Therapeutic Class

  • Glucocorticoids

Storage Conditions

  • Cool and dry place
  • Protected from light
  • Keep away from children

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