Pred 5 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Prednisolone |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Indications
- Rheumatic Disorders
- Endocrine Disorders
- Dermatologic Diseases
- Allergic States
- Respiratory Diseases
- Hematologic Disorders
- Edematous States
- Gastrointestinal Diseases
Pharmacology
Synthetic adrenocortical drug with predominantly glucocorticoid properties. Inhibits the action of the Phospholipase A2 enzyme. Rapidly absorbed from the gastrointestinal tract. Metabolized in the liver and excreted in the urine.
Dosage & Administration
- Adult:
- Nephrotic Syndrome
- Anti-inflammatory
- Acute Asthma
- Allergic Conditions
- Pediatric:
- Asthma
- Anti-inflammatory
- Immunosuppression
Interaction
Efficacy reduced by Aminoglutethimide, Antacids, Barbiturates, Carbamazepine, Griseofulvin, Mitotane, Phenylbutazone, Phenytoin, Primidone, and Rifampin. Reduces potassium levels. Digitalis can cause Cardiac arrhythmias if hypokalemia occurs. Immunization should be done carefully.
Contraindications
Systemic infections unless specific anti-infective therapy is employed. Hypersensitivity. Ocular herpes simplex.
Side Effects
- Increased appetite
- Indigestion
- Nervousness or restlessness
- Darkening or lightening of skin color
- Dizziness or lightheadedness
- Flushing of face or cheeks
- Hiccups
- Increased sweating
- Sensation of spinning
Pregnancy & Lactation
Not recommended during pregnancy unless essential. Should only be used if the expected benefit to the mother is greater than any possible risk to the fetus. Corticosteroids appear in breast milk and could suppress growth or cause unwanted effects.
Precautions & Warnings
Precaution in diabetes, hypertension, Psychological disturbances, osteoporosis, post-menopausal women, pregnancy, and chronic nephritis. Long-term use can cause Cushing's habitus, hyperglycemia, muscular weakness, increased susceptibility to infection, delayed wound healing, and psychiatric disturbances.
Overdose Effects
Adverse effects develop after prolonged use of doses in excess of the normal physiological requirement. Treatment is symptomatic and the dose should be reduced gradually.
Therapeutic Class
Glucocorticoids
Storage Conditions
Store in a cool and dry place, protected from light. Keep out of the reach of children.