Psudonil 100 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 16.05 (1 x 5: ৳ 80.25)

Medicine Details

Indications

  • Short-term treatment of serious infections
  • Treatment of bacterial septicemia
  • Treatment of respiratory tract infections
  • Treatment of bones and joints infections
  • Treatment of central nervous system infections
  • Treatment of skin and soft tissue infections
  • Treatment of intra-abdominal infections
  • Treatment of burns and postoperative infections
  • Effective in urinary tract infections
  • Effective in staphylococci infections

Pharmacology

  • Semi-synthetic aminoglycoside antibiotic
  • Active against pseudomonas species
  • Active against Escherichia coli
  • Active against Proteus species
  • Active against Providencia species
  • Active against Klebsiella-Enterobacter species
  • Active against Acinetobacter species
  • Active against Citrobacter freundii
  • Active in vitro against penicillinase and nonpenicillinase-producing Staphylococcus species

Dosage

  • Adult dosage
  • Children dosage
  • Neonates and premature children dosage
  • Elderly dosage
  • Recommendation for life-threatening infections
  • Recommendation for urinary tract infections
  • Dosage adjustment for impaired renal function

Administration

  • Intramuscular administration
  • Intravenous administration
  • Intraperitoneal use

Interaction

  • Concurrent administration with myorelaxants
  • Avoid combination with other Aminoglycoside antibiotics
  • Risk of ototoxicity with fast acting diuretics
  • Risk of nephrotoxicity with Cephalosporins or Polymixins

Contraindications

  • Hypersensitivity to Amikacin or any constituents of the injection

Side Effects

  • Tinnitus
  • Vertigo
  • Reversible or irreversible deafness
  • Skin rash
  • Drug fever
  • Headache
  • Paraesthesia
  • Nausea
  • Vomiting

Pregnancy & Lactation

  • Crosses placenta into the fetal circulation
  • Potential risk of ototoxicity in the fetus
  • No information available for safety during breastfeeding

Precautions & Warnings

  • High concentrations in the renal excretory system
  • Need for adequate hydration
  • Monitoring of renal function

Use in Special Populations

  • Safety and effectiveness not established in children or adolescents under 16 years

Overdose Effects

  • Peritoneal dialysis
  • Haemodialysis

Therapeutic Class

  • Aminoglycosides

Storage Conditions

  • Temperature below 30°C
  • Away from light
  • Away from moisture
  • Keep out of the reach of children

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