Solone 5 mg/5 ml (Oral Solution)

50 ml bottle: ৳ 65.00

Medicine Details

Category	Details
Generic	Prednisolone
Company	Aci limited
Also available as	Solone 10 mg tablet Solone 20 mg tablet Solone 5 mg tablet

Indications

Rheumatic Disorders
Endocrine Disorders
Dermatologic Diseases
Allergic States
Respiratory Diseases
Hematologic Disorders
Edematous States
Gastrointestinal Diseases

Pharmacology

Synthetic adrenocortical drug with predominantly glucocorticoid properties, inhibits the action of Phospholipase A2 enzyme, well absorbed from the gastrointestinal tract, metabolized in the liver and excreted in the urine

Dosage & Administration

Adult:
- Nephrotic Syndrome:
  - Initial: 2 mg/kg/day (maximum 80 mg/day) in divided doses 3 to 4 times/day
  - Maintenance dose: 0.5 to 1 mg/kg/dose given every other day for 3 to 6 months
- Anti-inflammatory: 5 to 60 mg per day in divided doses 1 to 4 times/day
- Acute Asthma: 40-60 mg/day PO in single daily dose or divided q12 hr for 3-10 days
- Allergic Conditions:
  - Day 1: 10 mg PO before breakfast, 5 mg after lunch and after dinner, and 10 mg at bedtime
  - Day 6: 5 mg PO before breakfast
Pediatric:
- Asthma:
  - 1 year: Acute: 10 mg orally every 12 hours
  - 12 years: Acute: 40 mg orally every 12 hours
- Anti-inflammatory: 0.05 to 2 mg/kg/day divided 1 to 4 times/day
- Immunosuppression: 0.05 to 2 mg/kg/day divided 1 to 4 times/day

Interaction

Efficacy reduced by Aminoglutethimide, Antacids, Barbiturates, Carbamazepine, etc. Solone reduces the amount of potassium in the blood. Immunization should be done carefully.

Contraindications

Systemic infections, Hypersensitivity to any ingredient, Ocular herpes simplex

Side Effects

Increased appetite
Indigestion
Nervousness or restlessness
Dizziness or lightheadedness
Increased sweating
The sensation of spinning

Pregnancy & Lactation

Not recommended during pregnancy unless considered essential by the doctor, can appear in breast milk

Precautions & Warnings

Precaution in diabetes, hypertension, Psychological disturbances, osteoporosis, post-menopausal women, pregnancy, and chronic nephritis

Overdose Effects

Adverse effects develop after prolonged use of doses in excess of the normal physiological requirement, treatment is symptomatic

Therapeutic Class

Glucocorticoids

Storage Conditions

Store in a cool and dry place, protected from light, Keep out of reach of children