Nutrimin-D 7%+10% (IV Infusion)

Title

• Nutrimin-D IV Infusion

Categories

• Medical Supplies
• Nutritional Supplements
• Parenteral Nutrition

Description

• Sterile aqueous solution of 7% amino acids IV infusion and 10% glucose with electrolytes
• Contains essential and non-essential amino acids needed for protein synthesis
• Promotes positive nitrogen balance in postoperative and extended intravenous nutrition periods
• Promotes protein synthesis and wound healing
• Reduces endogenous protein catabolism

Composition

• Essential amino acids: L-Isoleucine, L-Leucine, L-Lysine Hydrochloride, L-Methionine, L-Phenylalanine, L-Threonine, L-Tryptophan, L-Valine, L-Histidine, L-Tyrosine
• Non-essential amino acids: L-Arginine, L-Aspartic Acid, L-Glutamic Acid, L-Alanine, L-Cystine, Glycine, L-Proline, L-Serine
• Carbohydrate: Anhydrous Glucose
• Electrolytes: Sodium, Potassium, Calcium, Magnesium, Chloride

Indications

• Source of amino acids, glucose, and electrolytes in adult and pediatric patients needing IV nutrition
• Suitable for patients with basal amino acid requirements

Pharmacology

• A crystalline amino acid solution for promoting protein synthesis and wound healing
• Reduces endogenous protein catabolism
• Can be administered as part of total parenteral nutrition (TPN)

Dosage & Administration

• Adult dosage range: 0.10-0.25 g nitrogen/kg/day
• Infusion range: 11-27 ml/kg/day
• Slow infusion rate not exceeding 500 ml in 3 hours
• Infants & children: maximal rate of infusion of 30 ml/kg body weight/day

Interaction

• Expected not to interact with other medicaments at recommended dosage

Contraindications

• Inborn errors of amino acids metabolism
• Severe liver damage
• Severe uremia without available dialysis facilities
• Hyperosmolar nonketotic diabetic coma
• Known hypersensitivity to any of its ingredients

Side Effects

• Rarely: Nausea
• During infusion: Vomiting, flushing, sweating
• Transient increases in liver test
• Hypersensitivity reactions
• Thrombophlebitis when using peripheral veins

Pregnancy & Lactation

• Safe administration during pregnancy in humans reported
• No animal reproduction studies conducted

Precautions & Warnings

• Monitor phenylalanine level in severely ill, premature infants
• Use with caution in patients with diabetes mellitus, severe heart failure, or renal function issues
• Hyperglycemic patients may require exogenous insulin
• Do not use if solution is turbid or contains particles
• Discard any unused portion

Therapeutic Class

• Parenteral nutritional preparations

Storage Conditions

• Protect from light
• Store between 15°C to 25°C
• Avoid freezing
• Keep away from children

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