Pro-Medrol 500 mg/vial (IM/IV Injection)
500 mg vial: ৳ 600.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Methylprednisolone sodium succinate |
| Company | Techno drugs ltd |
| Also available as |
Indications
- Endocrine disorders
- Rheumatic disorders
- Collagen diseases
- Dermatological diseases
- Allergic states
- Ophthalmic diseases
- Gastrointestinal diseases
- Respiratory diseases
- Hematologic disorders
- Neoplastic diseases
- Edematous state
- Tuberculous meningitis
- Trichinosis with neurologic involvement
Pharmacology
- Potent anti-inflammatory effects
- Salt-retaining properties
- Excretion within 12 hours
- Influences metabolism and water balance
- Suppressive effect on the immune response
Dosage & Administration
- Administered by IM or IV
- High-dose therapy for 48 hours
- Decreased gradually after prolonged use
- Initial dose varies based on clinical problem
- Different initial dose for pediatric use
- Intravenous infusion over at least 30 minutes
Interactions
- Aminoglutethimide
- Amphotericin B and potassium-depleting agents
- Macrolide antibiotics
- Anticholinesterases
- Anticoagulants
- Antidiabetics
- Antitubercular drugs
- Cholestyramine
- Cyclosporine
- Digitalis glycosides
- Estrogens
- Hepatic Enzyme Inhibitors
- Ketoconazole
- Nonsteroidal anti-inflammatory agents
- Skin tests
- Vaccines
Contraindications
- Systemic fungal infections
- Known hypersensitivity
- Intrathecal administration
- Idiopathic thrombocytopenic purpura for intramuscular use
Side Effects
- Fluid and Electrolyte Disturbances
- Musculoskeletal adverse effects
- Gastrointestinal issues
- Dermatologic reactions
- Neurological effects
- Endocrine complications
- Ophthalmic reactions
- Negative nitrogen balance
- Other adverse reactions related to parenteral corticosteroid therapy
Pregnancy & Lactation
- Potential teratogenic effects
- Presence in human milk
- Potential for serious adverse reactions in nursing infants
Precautions & Warnings
- Sensitive to heat
- Use lowest possible dose
- Gradual reduction in dosage
- Observation for complications
- Consideration for dose and duration of treatment
- Risk/benefit decision
- Discontinuation may result in clinical improvement
Use in Special Populations
- Adverse effects in pediatric patients
- Observation for growth effects
- Caution in elderly patients
Overdose Effects
- Supportive and symptomatic therapy
Therapeutic Class
- Glucocorticoids
Reconstitution
- Directions for reconstitution
- Cleanse stopper with a suitable germicide
- Agitate to dissolve the powder content
- Use within 48 hours after mixing
Storage Conditions
- Protect from light
- Store at controlled room temperature
- Use solution within 48 hours after mixing